MRI: Acquisition of a high-field NMR spectrometer
MRI: Acquisition of a high-field NMR spectrometer
批准号:
0722654
负责人:
Andreas Franz
金额:
$52.35万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2007
资助国家:
美国
项目状态:
已结题
起止时间:
2007-08-15 至 2010-07-31
中文摘要
有了这项来自主要研究仪器计划(MRI)的奖项,太平洋大学化学系将获得一台500 MHz的NMR光谱仪。该光谱仪将用于研究项目,包括1)寡糖的结构测定,2)分子纳米开关的构象测定,以及3)纳米尺度超分子系统的结构和机理研究。该奖项的影响将影响到大量的少数民族学生,因为校园人口由60%的少数民族学生组成。核磁共振(NMR)光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质,表征分子内原子的特定排列,并研究溶液中分子之间相互作用的动力学。对于从事前沿研究的化学家来说,使用最先进的NMR光谱仪是必不可少的。来自这些高场NMR研究的结果将导致1)具有增加的信号分散的更高分辨率,2)用于计算建模的精确耦合信息和3)低浓度样品中相变的更可靠动力学研究。
英文摘要
With this award from the Major Research Instrumentation program (MRI), the Department of Chemistry at the University of the Pacific will acquire a 500 MHz NMR spectrometer. The spectrometer will be utilized in research projects including 1) structural determination of oligosaccharides, 2) conformation determination of molecular nano-switches, and 3) structural and mechanistic studies of nano-scale supramolecular systems. The impact of this award will affect a significant number of minority students as the campus population consists of 60% minority students. Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these high field NMR studies will result in 1) higher resolution with increased signal dispersion, 2) precise coupling information for computational modeling and 3) more reliable kinetic studies of phase-transitions in low concentration samples.
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