Fundamentals of Viscous Withdrawal, Flow-Focusing & Light-Driven Jetting
粘性撤回、流量聚焦的基础知识
基本信息
- 批准号:0730629
- 负责人:
- 金额:$ 14.5万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2007
- 资助国家:美国
- 起止时间:2007-09-01 至 2010-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
PROPOSAL NO.: CBET-0730629 PRINCIPAL INVESTIGATOR: ZHANG, WENDY W. INSTITUTION: UNIVERSITY OF CHICAGO FUNDAMENTALS OF VISCOUS WITHDRAWAL, FLOW-FOCUSING & LIGHT-DRIVEN JETTINGNew engineering processes can manipulate small amounts of liquid with accuracy and speed. Such techniques make possible new materials whose textures are controlled on micron to sub-micron scales. A theoretical/numerical analysis will elucidate the interaction between bulk flow and interface deformation. Focus will be on three example problems: viscous entrainment, cell encapsulation and light-induced jetting. All three have direct technological relevance. The entrainment of a viscous liquid can be manipulated to create thin, stable micron-sized spouts. This is a crucial step in the manufacture of fibers and wires. Thin spouts can also coat irregularly-shaped solid particles uniformly. In particular, it currently encapsulates insulin-producing Islets in an effort to develop a transplant therapy for type I diabetes. Light-induced jetting offers a way to produce and transport small amounts of liquid using entirely light from a laser beam, without the need of pre-fabricated microchannels. The PI will analyze these questions within a common framework characterizing the interaction between viscous flow and surface deformation. Building on prior work successfully modeling the interface deformation produced by a converging flow will help develop simple, asymptotic models for the processes and also numerical models for quantitative comparisons to experiments. Broader impacts include quantitative analyses on the dynamics to determine the speed attained by a rising bubble in a liquid-lined tube has been instrumental in the development of medical treatments for airway closure, and in current development of microfluidic devices. Results obtained from this analysis are likely to be relevant to formation of compound fibers in electrical spinning, the manufacture of droplets, capsules and photonic band gap materials via flow-focusing in microfluidic channels. This research will also be incorporated into science education on several different levels. The analysis of simulation results, in particular the comparison between the simulation results and the experimental measurements, will be part of the summer undergraduate/high-school student research program sponsored by the Physics department at the University of Chicago. Some of the broader issues raised by this research, in particular the connection between fundamental fluid dynamics and technological challenges in bio-medical engineering and nanotechnology, will be explored in the graduate and undergraduate courses on fluid dynamics.
提案编号:CBET-0730629主要制造商:ZHANG,WENDY W.研究机构:芝加哥大学粘性流体力学基础,流动聚焦光驱动喷射新的工程工艺可以精确和快速地操纵少量液体。这种技术使得纹理控制在微米到亚微米尺度上的新材料成为可能。理论/数值分析将阐明整体流动和界面变形之间的相互作用。重点将放在三个例子的问题:粘性夹带,细胞封装和光诱导喷射。这三个方面都具有直接的技术相关性。粘性液体的夹带可以被操纵以产生薄的、稳定的微米尺寸的喷口。这是制造纤维和电线的关键步骤。薄喷口也可以均匀地涂覆不规则形状的固体颗粒。特别是,它目前封装了产生胰岛素的胰岛,以努力开发I型糖尿病的移植疗法。光诱导喷射提供了一种完全使用来自激光束的光来生产和运输少量液体的方法,而不需要预制的微通道。PI将在一个共同的框架内分析这些问题,以表征粘性流和表面变形之间的相互作用。建立在以前的工作成功地模拟界面变形所产生的收敛流将有助于开发简单的,渐近模型的过程中,也定量比较实验的数值模型。更广泛的影响包括对动力学的定量分析,以确定由液体内衬管中的上升气泡所获得的速度,这在气道闭合的医学治疗的发展中以及在微流体装置的当前发展中是有用的。从这个分析中获得的结果可能是相关的复合纤维的形成,在电纺丝,液滴,胶囊和光子带隙材料的制造通过在微流体通道中的流动聚焦。这项研究还将纳入不同层次的科学教育。模拟结果的分析,特别是模拟结果和实验测量之间的比较,将是夏季本科生/高中生研究计划的一部分,由芝加哥大学物理系赞助。这项研究提出的一些更广泛的问题,特别是基本流体动力学和生物医学工程和纳米技术的技术挑战之间的联系,将在流体动力学的研究生和本科课程中进行探讨。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Wendy Zhang其他文献
Considerations for Culturally Appropriate HIV/AIDS Education Strategies in Belize: An Analytical Study Exploring the Relationship Between Knowledge and Stigma
伯利兹文化上适当的艾滋病毒/艾滋病教育策略的考虑:一项探索知识与耻辱之间关系的分析研究
- DOI:
10.4172/2155-6113.1000369 - 发表时间:
2010 - 期刊:
- 影响因子:0
- 作者:
C. McInnes;Treena R Orchard;PhDb;E. Druyts;Reon Baird;PhDc;Wendy Zhang;PhDb Robert S. Hogg;Pamela VanDeusenc - 通讯作者:
Pamela VanDeusenc
Direct-to-Consumer Genetic Ancestry Testing in Clinical Encounters: Perspectives From Psychotherapy Cases (Preprint)
临床遭遇中直接面向消费者的基因祖先测试:心理治疗案例的视角(预印本)
- DOI:
- 发表时间:
2020 - 期刊:
- 影响因子:0
- 作者:
C. Rubanovich;Wendy Zhang;C. Bloss - 通讯作者:
C. Bloss
Durability of non-nucleotide reverse transcriptase inhibitor-based first-line ART regimens after 7 years of treatment in rural Uganda
乌干达农村地区基于非核苷酸逆转录酶抑制剂的一线 ART 方案治疗 7 年后的持久性
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:1.6
- 作者:
M. Nanfuka;Jamie I. Forrest;Wendy Zhang;S. Okoboi;J. Birungi;P. Kaleebu;Julia Zhu;Samuel Tibenganas;D. Moore - 通讯作者:
D. Moore
The Role of ALS8-linked VAMP-associated Protein B (VAPB) in Caenorhabditis elegans Motor Neurons
ALS8 连接的 VAMP 相关蛋白 B (VAPB) 在秀丽隐杆线虫运动神经元中的作用
- DOI:
10.20381/ruor-3905 - 发表时间:
2015 - 期刊:
- 影响因子:4
- 作者:
Wendy Zhang - 通讯作者:
Wendy Zhang
A Latent Class Analysis of the Social Determinants of Health Impacting Heavy Alcohol Consumption Among Women Living with HIV in Canada: The Canadian HIV Women’s Sexual and Reproductive Health Cohort Study
影响加拿大艾滋病毒感染者重度饮酒的健康社会决定因素的潜在类别分析:加拿大艾滋病毒妇女性健康和生殖健康队列研究
- DOI:
10.1007/s10461-019-02454-3 - 发表时间:
2019 - 期刊:
- 影响因子:4.4
- 作者:
M. Shokoohi;Greta R. Bauer;A. Kaida;C. Logie;A. Carter;A. Lacombe;M. Loutfy;Rahma Aranka Jonathan Jean;Rahma Abdul;A. Anema;J. Angel;J. Baril;Fatimatou Barry;Kerrigan Beaver;Denise Becker;Anita C. Benoit;J. Brophy;L. Brotto;A. Burchell;Claudette Cardinal;Allison Carlson;A. Carter;A. Cescon;L. Cioppa;Jeffrey Cohen;G. Colley;Tracey Conway;C. Cooper;Jasmine Cotnam;J. Cousineau;Janice Dayle;M. Desbiens;Hania Dubinsky;D. Dubuc;J. Duddy;Brenda Gagnier;J. Gahagan;Claudine Gasingirwa;N. Gataric;S. Greene;T. Hart;C. Hankins;B. Hogg;Terry Howard;Shazia Islam;Evin Jones;C. Kaushic;A. Keating;Logan Kennedy;M. Kestler;Maxime Kiboyogo;M. Klein;G. Kwaramba;A. Langlois;Melanie Lee;Rebecca Lee;L. Leonard;Johanna Lewis;V. Lima;E. Lloyd;C. Logie;Shari Margolese;Carrie Martin;R. Masching;Lyne Massie;Melissa Medjuck;Brigitte Ménard;Cari Miller;D. Money;M. Muchenje;Mary Mwalwanda;Mary Ndung’u;V. Nicholson;Illuminée Nzikwikiza;Kelly K. O’Brien;N. O'Brien;G. Ogilvie;S. Ogunnaike;J. Otis;A. Palmer;S. Patterson;Doris Peltier;Yasmeen Persad;N. Pick;A. Pierre;J. Powis;Karène Proulx;Corinna M. Quan;J. Raboud;A. Rachlis;Edward D. Ralph;Stephanie Rawson;E. Roth;D. Rouleau;S. Rourke;S. Rueda;M. Saavedra;K. Salters;Margarite Sánchez;R. Sandre;Jacquie Sas;P. Sereda;F. Smaill;Stephanie S. Smith;Marcie Summers;Tsitsi Tigere;W. Tharao;Jamie Thomas;Christina Tom;C. Tremblay;B. Trottier;S. Trottier;C. Tsoukas;A. Wagner;S. Walmsley;K. Webster;W. Wobeser;Jessica Yee;M. Yudin;Wendy Zhang - 通讯作者:
Wendy Zhang
Wendy Zhang的其他文献
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{{ truncateString('Wendy Zhang', 18)}}的其他基金
Inertial jets from cavity collapse & granular impact
空腔塌陷产生的惯性射流
- 批准号:
0967282 - 财政年份:2010
- 资助金额:
$ 14.5万 - 项目类别:
Continuing Grant
CPATH-1: Collaborative Research: A Verification-Driven Learning Model that Enriches CS and Related Undergraduate Programs
CPATH-1:协作研究:一种验证驱动的学习模型,丰富计算机科学和相关本科课程
- 批准号:
0939015 - 财政年份:2009
- 资助金额:
$ 14.5万 - 项目类别:
Standard Grant
Finite-time Singularities and Fluid Withdrawal
有限时间奇点和流体抽取
- 批准号:
0102033 - 财政年份:2001
- 资助金额:
$ 14.5万 - 项目类别:
Fellowship Award
Microstructural Evolution in Sintering - Experimental, Mathematical and Numerical Study
烧结过程中的微观结构演变 - 实验、数学和数值研究
- 批准号:
9996087 - 财政年份:1998
- 资助金额:
$ 14.5万 - 项目类别:
Continuing Grant
Microstructural Evolution in Sintering - Experimental, Mathematical and Numerical Study
烧结过程中的微观结构演变 - 实验、数学和数值研究
- 批准号:
9705849 - 财政年份:1997
- 资助金额:
$ 14.5万 - 项目类别:
Continuing Grant
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