Workshop: Quantitative Approaches to Early Development, Tempe, AZ, May 20-23, 2007

摘要“研讨会：早期发育的定量方法”生物学中最大的挑战之一是理解早期胚胎细胞之间的复杂相互作用如何导致协调生长、形态和功能。为了追求这种理解，科学家们越来越多地转向定量方法，以补充基于遗传操作和显微镜的实验方法。量化方法论的灵感来自几个学科的工作。例子包括时间分辨显微镜、协调细胞运动的速度图、计算机模拟和数学/生物物理模型。为这些量化方法的先驱科学家创造新的机会，让他们聚在一起，学习彼此的工作，这一点很重要，也很及时。本次研讨会于2007年5月20日至23日在亚利桑那州坦佩举行，旨在提供这样的机会。它将汇集这一领域一些世界顶尖科学家的精选小组。确定的群体包括具有细胞和发育生物学背景的科学家，以及物理、数学和工程学背景的科学家。所有人都在定量可视化、实验和计算建模的各个方面拥有独特的专业知识，并应用于早期开发。研讨会由亚利桑那州立大学的蒂莫西·纽曼和英国邓迪大学的科尼利厄斯·韦杰共同组织，并将由亚利桑那州立大学生物物理中心(蒂莫西·纽曼是该中心的创始成员)和国家科学基金会的综合组织系统司联合资助。会议将由一系列高度集中和亲密的会议组成。会议将向来自亚利桑那州立大学和亚利桑那大学的当地与会者开放，并将鼓励研究生出席。为了确保更广泛的影响，特别是在对外地毕业生和博士后的教育方面，我们将维持一个网站，在该网站上张贴每位发言者发言的视频和POWER POINT副本以及讨论记录。

Abstract for "Workshop: Quantitative Approaches to Early Development" One of the greatest challenges in biology is to understand how the complex interactions between cells in the early embryo lead to coordinated growth, form, and function. In pursuit of this understanding, scientists are increasingly turning to quantitative methodologies to complement experimental approaches based on genetic manipulations and microscopy. Quantitative methodologies are inspired by work from several disciplines. Examples include time-resolved microscopy, velocity-maps of coordinated cell movement, computer simulations, and mathematical/biophysical modeling. It is important and timely to create novel opportunities for scientists who are pioneering these quantitative approaches to meet together and learn of each others' work. This workshop in Tempe, Arizona during May 20th-23rd, 2007, is designed to provide such an opportunity. It will bring together a select group of some of the world's leading scientists in this area. The group identified includes scientists with backgrounds in cell and developmental biology, as well as physics, mathematics, and engineering. All have unique expertise in various aspects of quantitative visualization, experimentation, and computational modeling, with application to early development. The workshop is co-organized by Timothy Newman (ASU) and Cornelius Weijer (University of Dundee, UK), and will be jointly funded by the ASU Center for Biological Physics (of which Timothy Newman is a founding member) and the Division of Integrative Organismal Systems at the National Science Foundation. The meeting will consist of a set of highly focused and intimate sessions. The meeting will be open to local attendees from Arizona State University and the University of Arizona, and will encourage graduate student attendance. To ensure broader impact, especially in terms of education for graduates and postdocs in the field, we will maintain a website on which both video and power point copies of each speaker's talk will be posted, along with transcripts of discussions.