PSCIC Full Proposal: The iPlant Collaborative: A Cyberinfrastructure-Centered Community for a New Plant Biology

PSIC 完整提案:iPlant 协作:以网络基础设施为中心的新植物生物学社区

基本信息

  • 批准号:
    0735191
  • 负责人:
  • 金额:
    $ 5000万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Cooperative Agreement
  • 财政年份:
    2008
  • 资助国家:
    美国
  • 起止时间:
    2008-02-01 至 2014-01-31
  • 项目状态:
    已结题

项目摘要

University of Arizona: Richard Jorgensen (PI), Gregory Andrews, Kobus Barnard, Susan Brown, Vicki Chandler, Nirav Merchant, Carolyn Napoli, Sudha Ram, Steven RounsleyArizona State University: Daniel StanzioneCold Spring Harbor Laboratory: Lincoln Stein, Doreen WarePurdue University: Rebecca Doerge, University of North Carolina at Wilmington: Ann StapletonThe iPlant Collaborative (iPC) is a new type of organization ? a cyberinfrastructure collaborative for the plant sciences - that enables new conceptual advances through integrative, computational thinking (i.e. thinking at multiple levels of abstraction using a systems-level approach to problem-solving). The iPC is fluid and dynamic, utilizing new computer, computational science and cyberinfrastructure solutions to address an evolving array of grand challenges in the plant sciences. It is community-driven, involving plant biologists, computer and information scientists and engineers, as well as experts from other disciplines, all working in integrated teams. The iPC brings together strengths in plant biology, bioinformatics, statistics, computer science and high throughput computing, as well as innovative approaches to education, outreach, and the study of social networks.Several key principles guided the development of the iPC. Specifically, the iPC:? is a cyberinfrastructure collaborative rather than purely a cyberinfrastructure,? will enable multi-disciplinary teams to address grand challenges in plant science,? will be an entity that is by, for and of the community,? will train the next generation in computational thinking, and? is designed to be able to reinvent itself as needs and technologies change.The driving force behind the iPC is the nature of the grand challenge questions in plant sciences, and all facets of the collaborative are organized around those selected questions. The act of selecting these questions will be community-driven, and to facilitate that, the Collaborative will host a series of workshops, each focused on a specific area of plant biology, but with participants cutting across the spectrum of the computational and biological sciences. The goal of each workshop will be to identify the grand challenge questions in that field, as well as the necessary strategies and approaches that will be needed to solve the question(s). Self-forming Grand Challenge Teams from the community will then work with iPC personnel to develop a ?Discovery Environment? (DE), which will be a cyberinfrastructure for open-access research and education focused on a grand challenge question. Over time, the DEs designed for different grand challenges will overlap and coalesce into a comprehensive cyberinfrastructure for discovery and learning.The cyberinfrastructure created by the iPC will provide the community with two main capabilities: it will provide access to world-class physical infrastructure ? for example persistent storage, and compute power via local and national resources, and it will provide services that promote interactions, communications and collaborations and that advance the understanding and use of computational thinking in plant biology. Through these capabilities, the iPC will catalyze progress in targeted areas of plant biology, and more broadly advance the whole of plant science through new, creative, synthesis activities, and training the next generation of scientists in computational (and collaborative) thinking.The broader impacts of the iPC project will not be limited merely to creating the tools for solution of currently intractable grand challenge questions, because at its core the iPC is actually a community building and educational enterprise designed to facilitate education and outreach. Grand Challenge teams and iPC staff will work together to educate students (K-12, undergraduate, and graduate, including members of underrepresented groups) through the use and development of Discovery Environments. Thus, education and outreach efforts will permeate the iPlant Collaborative.
亚利桑那大学:理查德·乔根森(PI),格雷戈里·安德鲁斯,科布斯·巴纳德,苏珊·布朗,维奇·钱德勒,尼拉夫·莫奇特,卡罗琳·那不勒斯,苏达·拉姆,史蒂文·朗斯利亚利桑那州立大学:丹尼尔·斯坦齐恩冷泉港实验室:林肯·斯坦,多琳·韦尔普渡大学:丽贝卡·多丽丝,威尔明顿的北卡罗来纳州大学:安·斯台普顿iPlant协作组织(iPC)是一种新型的组织?植物科学的网络基础设施协作-通过综合计算思维(即使用系统级方法解决问题,在多个抽象层次上进行思维)实现新的概念进步。iPC是流动和动态的,利用新的计算机,计算科学和网络基础设施解决方案来解决植物科学中不断变化的一系列重大挑战。 它是由社区驱动的,涉及植物生物学家、计算机和信息科学家和工程师,以及来自其他学科的专家,所有人都在综合团队中工作。iPC汇集了植物生物学、生物信息学、统计学、计算机科学和高通量计算方面的优势,以及教育、推广和社交网络研究的创新方法。 具体来说,iPC:?网络基础设施是协作性的,而不是纯粹的网络基础设施?将使多学科团队能够应对植物科学的重大挑战,?将是一个由社区组成,为社区服务,为社区服务的实体。将培养下一代的计算思维,而且?iPC旨在能够随着需求和技术的变化而重塑自身。iPC背后的驱动力是植物科学中重大挑战问题的性质,并且围绕这些选定的问题组织合作的各个方面。 选择这些问题的行为将是社区驱动的,为了促进这一点,协作将举办一系列研讨会,每个研讨会都侧重于植物生物学的一个特定领域,但参与者跨越计算和生物科学的范围。 每个讲习班的目标都是确定该领域的重大挑战问题,以及解决这些问题所需的必要战略和办法。然后,来自社区的自组大挑战团队将与iPC人员合作开发一个?探索环境?(DE),这将是一个开放获取研究和教育的网络基础设施,专注于一个重大的挑战问题。 随着时间的推移,为不同的重大挑战而设计的DE将重叠并合并为一个用于发现和学习的综合网络基础设施。例如永久性存储,以及通过当地和国家资源的计算能力,它将提供促进互动、通信和合作的服务,并促进对植物生物学中计算思维的理解和使用。通过这些能力,iPC将促进植物生物学目标领域的进展,并通过新的、创造性的综合活动,更广泛地推动整个植物科学的发展,并培养下一代计算科学家。iPC项目的更广泛影响将不仅限于为解决当前棘手的重大挑战问题创造工具,因为iPC的核心实际上是一个社区建设和教育企业,旨在促进教育和推广。Grand Challenge团队和iPC工作人员将共同努力,通过使用和开发Discovery Environments来教育学生(K-12,本科生和研究生,包括代表性不足的群体成员)。因此,教育和外联工作将渗透到iPlant Collaborative。

项目成果

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Stephen Goff其他文献

Turkey must end violent response to protests.
土耳其必须停止对抗议活动的暴力反应。
  • DOI:
  • 发表时间:
    2013
  • 期刊:
  • 影响因子:
    56.9
  • 作者:
    Emrah Altindis;M. Alpar;Emre R F Aksay;J. Beckwith;Christian Bökel;R. Curl;R. Darnell;S. Elledge;B. Erman;J. Frahm;Stephen Goff;P. Greengard;Roald Hoffmann;Bayazit Ilhan;J. Kaslin;S. Lipkin;C. Poulopoulou;Erez Raz;Mark Rubin;Mehmet Salturk;R. Schrock;A. Trautmann;D. Unutmaz;H. Weinstein;Caghan Kizil
  • 通讯作者:
    Caghan Kizil
Retroviral reverse transcriptase: synthesis, structure, and function.
TPO and IL-3 induce overlapping but distinct protein tyrosine phosphorylation in a myeloid precursor cell line.
TPO 和 IL-3 在骨髓前体细胞系中诱导重叠但不同的蛋白质酪氨酸磷酸化。
Transfer and Expression of the Human Multiple Drug Resistance Gene in Human CD34<sup>+</sup> Cells
  • DOI:
    10.1182/blood.v84.5.1408.1408
  • 发表时间:
    1994-09-01
  • 期刊:
  • 影响因子:
  • 作者:
    Maureen Ward;Christine Richardson;Patricia Pioli;Larry Smith;Silvio Podda;Stephen Goff;Charles Hesdorffer;Arthur Bank
  • 通讯作者:
    Arthur Bank

Stephen Goff的其他文献

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{{ truncateString('Stephen Goff', 18)}}的其他基金

EAGER: The molecular basis of aging: The role of allele-specific gene expression, protein folding, and protein stability on the progression of aging
EAGER:衰老的分子基础:等位基因特异性基因表达、蛋白质折叠和蛋白质稳定性对衰老进程的作用
  • 批准号:
    1248090
  • 财政年份:
    2012
  • 资助金额:
    $ 5000万
  • 项目类别:
    Standard Grant

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