Luminactive Gold Complexes: Synthesis and Photophysics

发光金配合物：合成和光物理学

• 批准号: 0749086
• 负责人: Thomas Gray
• 金额: $ 37.5万
• 依托单位: Case Western Reserve University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0749086&HistoricalAwards=false
• 关键词: Luminactive; Gold; Complexes; Synthesis; Photophysics

This award in the Inorganic, Bioinorganic and Organometallic Chemistry program supports research by Professor Thomas G. Gray at Case Western Reserve University that emphasizes the organometallic chemistry and excited-state properties of gold(I). The leading objective is emplacement of gold(I) centers onto fluorescent organic molecules. The heavy-atom effect of gold opens access to the fluorophores' triplet-state photochemistry and photophysics. Gold can be introduced in sensitive, conjugated molecules that absorb at preordained wavelengths. Two new synthetic methods are demonstrated where gold(I) fragments are attached to aromatic skeletons through carbon-gold sigma bonds. The first of these, base-promoted transmetallation, binds gold to the peripheries of aromatic molecules and is broadly general and functionally tolerant. The second is a [3 + 2] cycloaddition reaction of gold(I) azides with terminal alkynes that yields gold(I) triazolato moieties. Photophysical studies, which include static and time- resolved emission measurements, demonstrate triplet-state luminescence from aromatics functionalized with gold. The synthesis concepts that underlie these activities permit measurement of both internal heavy-atom effects (through direct carbon-gold attachment) and of external effects, where gold is suspended above an emitting moiety upon a photoinert spacer. A variety of day-to-day applications call for materials that are robust, tunable triplet-state emitters. Among these are light-emitting diode technology, photosensitization, and biological labeling. This research will also contribute to chemical pedagogy through the development of an undergraduate laboratory exercise in the synthesis and characterization of group 11 complexes of azadipyrromethene chromophores. This research is also training undergraduate and graduate students for scientific careers in industry, government, the military, and academia.

这个奖项在无机，生物无机和有机化学计划支持研究教授托马斯G。格雷在凯斯西储大学，强调有机金属化学和金的激发态性质（I）。 主要目标是将金（I）中心安置到荧光有机分子上。 金的重原子效应开启了对荧光团三重态光化学和光物理学的研究。 金可以引入到敏感的共轭分子中，这些分子在预定的波长下吸收。 证明了两种新的合成方法，其中金（I）片段通过碳-金σ键连接到芳族骨架。 其中第一个是碱促进的transmetabolism，将金结合到芳香分子的外围，并且具有广泛的通用性和功能耐受性。 第二种是叠氮化金（I）与末端炔的[3 + 2]环加成反应，产生金（I）三唑部分。 包括静态和时间分辨发射测量的光物理研究证明了来自用金官能化的芳族化合物的三重态发光。 这些活动的基础的合成概念允许测量内部重原子效应（通过直接碳-金连接）和外部效应，其中金悬浮在光惰性间隔物上的发射部分上方。 各种各样的日常应用要求材料是鲁棒的、可调谐的三重态发射体。 其中包括发光二极管技术、光敏化和生物标记。 这项研究也将有助于化学教学，通过发展本科实验室练习的合成和表征组11复合物的氮杂二吡咯亚甲基发色团。 这项研究也在为工业、政府、军队和学术界的科学事业培养本科生和研究生。