Organic Functional Groups in Templated Solid-State Reactions

该奖项由材料研究部固态材料化学项目授予爱荷华大学，旨在将有机基团纳入模板反应中，该反应使用有机固态光化学进行。主要目标是开发将小（如乙烯基）和大（如t-丁基）基团以及羧酸纳入模板反应的方法，并构建修饰目标，如环烷和阶梯烷。该项目的其他目标是利用有机模板开发和详细指导这些光反应，以实现：a)荧光发射的可调变化；b)通过阴离子交换实现金属有机多面体的非共价功能化。该项目首次尝试系统地将有机功能整合到一种可靠的方法中，以控制晶体状态下的双分子反应性。这个项目的成功可以导致设计，无溶剂合成复杂分子和材料具有可调的性质。此外，本项目中建立的结构-性质关系也可以应用于其他固态反应。拟议的教育活动将包括通过开发一个无机实验室实验课程，将拟议的研究活动整合到本科课程中，该课程侧重于单晶到单晶的转化。作为拓展教育活动的一部分，？周末工作吗?关于x射线晶体学和粉末衍射的讲习班将扩大到包括讲座和实验。这项外联活动将通过网络基础设施和发展一个流动x光单位来扩大。已发表的有机实验，以及新的无机实验课程，将透过教育网站的互联网，以电子方式发放给本地学院的学生和教师。该网站正在由PI进一步开发，以使其可用于超分子化学的实验室实验。

This award to University of Iowa by the Solid State Materials Chemistry program in the Division of Materials Research is to incorporate organic groups into templated reactions, which are carried out using organic solid state photochemistry. Major goal is to develop methods to incorporate small (e.g. vinyl) and large (e.g. t-butyl) groups, as well as carboxylic acids into the templated reactions, and to construct decorated targets such as cyclophanes and ladderanes. Other aims of the project are to exploit and elaborate to direct these photoreactions using organic templates to make: a) tunable changes in fluorescence emission; and b) non-covalent functionalization of metal-organic polyhedra via anion exchange. This project represents a first attempt to systematically integrate organic functionalities into a dependable method to control bimolecular reactivity in the crystalline state. Success of this project can lead to the designed, solvent-free synthesis of complex molecules and materials with tunable properties. In addition, structure-property relationships developed in this project could also be applied to additional solid-state reactions.The proposed educational activities will involve integration of the proposed research activities into the undergraduate curriculum by developing an inorganic laboratory experiment course that focuses upon single-crystal-to-single-crystal transformations. As part of outreach educational activities, ?Working Weekends? workshops on X-ray crystallography and powder diffraction will be expanded to include both lectures and experiments. This outreach activity will be extended via cyberinfrastructure and through the development of a mobile X-ray unit. A published organic laboratory experiment, as well as a new inorganic experiment course will be disseminated electronically to students and faculty members of the local area colleges via the internet on the educational website. This website is being further developed by the PI to make it available for laboratory experiments in supramolecular chemistry.