Organic Functional Groups in Templated Solid-State Reactions

该奖项由材料研究部的固态材料化学计划授予爱荷华州大学，该计划将有机基团纳入模板反应中，该反应使用有机固态光化学进行。 主要目标是开发将小的（例如乙烯基）和大的（例如叔丁基）基团以及羧酸引入模板化反应中的方法，并构建修饰的目标，如环番和梯形。该项目的其他目的是利用和阐述使用有机模板来指导这些光反应，以：a）荧光发射的可调变化;和B）通过阴离子交换对金属有机多面体进行非共价官能化。该项目首次尝试将有机官能团系统地整合到一种可靠的方法中，以控制结晶状态下的双分子反应性。该项目的成功可以导致设计，无溶剂合成具有可调性能的复杂分子和材料。此外，本计画所发展的结构-性质关系也可应用于其他固态反应。建议的教育活动将透过发展以单晶至单晶转变为重点的无机实验室实验课程，将建议的研究活动整合至本科课程。作为推广教育活动的一部分，？周末工作？关于X射线晶体学和粉末衍射的讲习班将扩大到包括讲座和实验。将通过网络基础设施和开发一个移动的X光机来扩大这一外联活动。 一个出版的有机实验室实验，以及一个新的无机实验课程将通过教育网站上的互联网以电子方式传播给当地学院的学生和教职员工。PI正在进一步开发该网站，使其可用于超分子化学的实验室实验。

This award to University of Iowa by the Solid State Materials Chemistry program in the Division of Materials Research is to incorporate organic groups into templated reactions, which are carried out using organic solid state photochemistry. Major goal is to develop methods to incorporate small (e.g. vinyl) and large (e.g. t-butyl) groups, as well as carboxylic acids into the templated reactions, and to construct decorated targets such as cyclophanes and ladderanes. Other aims of the project are to exploit and elaborate to direct these photoreactions using organic templates to make: a) tunable changes in fluorescence emission; and b) non-covalent functionalization of metal-organic polyhedra via anion exchange. This project represents a first attempt to systematically integrate organic functionalities into a dependable method to control bimolecular reactivity in the crystalline state. Success of this project can lead to the designed, solvent-free synthesis of complex molecules and materials with tunable properties. In addition, structure-property relationships developed in this project could also be applied to additional solid-state reactions.The proposed educational activities will involve integration of the proposed research activities into the undergraduate curriculum by developing an inorganic laboratory experiment course that focuses upon single-crystal-to-single-crystal transformations. As part of outreach educational activities, ?Working Weekends? workshops on X-ray crystallography and powder diffraction will be expanded to include both lectures and experiments. This outreach activity will be extended via cyberinfrastructure and through the development of a mobile X-ray unit. A published organic laboratory experiment, as well as a new inorganic experiment course will be disseminated electronically to students and faculty members of the local area colleges via the internet on the educational website. This website is being further developed by the PI to make it available for laboratory experiments in supramolecular chemistry.