Organic Functional Groups in Templated Solid-State Reactions

这项由材料研究部固态材料化学项目授予爱荷华大学的奖项是将有机基团加入到使用有机固态光化学进行的模板化反应中。主要目标是开发在模板化反应中加入小基团(如乙烯基)和大基团(如叔丁基)以及羧酸的方法，并构建环烷和梯烷等装饰目标。该项目的其他目标是开发和详细说明使用有机模板指导这些光反应，以实现：a)荧光发射的可调变化；以及b)通过阴离子交换对金属-有机多面体进行非共价功能化。该项目是首次尝试系统地将有机功能集成到一种可靠的方法中，以控制结晶状态下的双分子反应性。该项目的成功可以导致设计的、无溶剂的复杂分子和具有可调性能的材料的合成。此外，在这个项目中开发的结构-性质关系也可以应用于更多的固态反应。拟议的教育活动将包括通过开发一门专注于单晶到单晶转变的无机实验室实验课程，将拟议的研究活动整合到本科课程中。作为外展教育活动的一部分，周末加班？关于X射线结晶学和粉末衍射的工作坊将扩大到包括讲座和实验。这一外联活动将通过网络基础设施和开发流动X光机得到扩展。已出版的有机实验室实验以及新的无机实验课程将通过教育网站上的互联网以电子方式分发给当地大学的学生和教职员工。该网站正在由国际和平研究所进一步开发，以供超分子化学的实验室实验使用。

This award to University of Iowa by the Solid State Materials Chemistry program in the Division of Materials Research is to incorporate organic groups into templated reactions, which are carried out using organic solid state photochemistry. Major goal is to develop methods to incorporate small (e.g. vinyl) and large (e.g. t-butyl) groups, as well as carboxylic acids into the templated reactions, and to construct decorated targets such as cyclophanes and ladderanes. Other aims of the project are to exploit and elaborate to direct these photoreactions using organic templates to make: a) tunable changes in fluorescence emission; and b) non-covalent functionalization of metal-organic polyhedra via anion exchange. This project represents a first attempt to systematically integrate organic functionalities into a dependable method to control bimolecular reactivity in the crystalline state. Success of this project can lead to the designed, solvent-free synthesis of complex molecules and materials with tunable properties. In addition, structure-property relationships developed in this project could also be applied to additional solid-state reactions.The proposed educational activities will involve integration of the proposed research activities into the undergraduate curriculum by developing an inorganic laboratory experiment course that focuses upon single-crystal-to-single-crystal transformations. As part of outreach educational activities, ?Working Weekends? workshops on X-ray crystallography and powder diffraction will be expanded to include both lectures and experiments. This outreach activity will be extended via cyberinfrastructure and through the development of a mobile X-ray unit. A published organic laboratory experiment, as well as a new inorganic experiment course will be disseminated electronically to students and faculty members of the local area colleges via the internet on the educational website. This website is being further developed by the PI to make it available for laboratory experiments in supramolecular chemistry.