National Institute for Mathematical and Biological Synthesis (NIMBioS)

该奖项建立了一个中心，以促进数学和生物科学接口的研究和教育。该中心的目标是解决基础和应用生物学问题，同时推进数学科学，并促进跨学科研究人员的发展。一个跨学科的观点，连接生物学的物理和社会科学，需要推动现代生物学沿着一系列广泛的挑战性问题，同时提供途径，在数学的根本进步。该中心将发展一系列小型工作组，重点关注通过向整个社区公开呼吁从跨学科努力中受益的主题，使该中心真正成为国家社区资源。这些努力有可能改变数学家和生物学家的合作方式，这种文化变革将推动这两个学科及其界面的重大进展。在过去的世纪里，生物学已经从主要描述生物世界的模式转变为确定这些模式是如何产生的，什么过程会影响它们，以及我们如何有效地修改和管理它们。通过与政府和行业合作伙伴的合作，该中心将为入侵物种的控制、限制传染病的影响以及提出药物设计的新方法等问题提供科学见解。因此，该中心将产生有助于制定国家政策的新知识。从K-12学生到博士后学者的各级教育举措将说明数学与生物学各个领域的联系，并将培养新一代数学生物学家。这些努力将以需要扩大在生物和数学科学中代表性不足的群体的参与为指导。该中心将通过与国家公园管理局建立重要的伙伴关系和开展研究合作，以大烟山国家公园的游客为对象，开展强有力的公共宣传工作。

This award establishes a Center to foster research and education at the interface of the mathematical and biological sciences. The goals of the Center are to address fundamental and applied biological questions while advancing the mathematical sciences, and to foster the development of transdisciplinary researchers. An interdisciplinary perspective, linking biology to the physical and social sciences, is needed to advance modern biology along a broad array of challenging problems while providing avenues for fundamental advances in mathematics. The Center will develop a series of small working groups focused on topics that will benefit from interdisciplinary efforts through an open call to the entire community so as to make the center truly a national community resource. These efforts have the potential to transform the way that mathematicians and biologists collaborate, a cultural change that will spur significant progress in both disciplines and at their interface. Over the past century biology has changed from mostly describing the patterns of the living world to determining how these patterns arose, what processes affect them and how we might effectively modify and manage them. In collaboration with government and industry partners, the Center will provide scientific insights into problems such as the control of invasive species, limiting impacts of infectious diseases, and suggesting new methods for drug design. Thus the Center will produce new knowledge that will help to shape national policy. Educational initiatives at all levels, from K-12 students to post-doctoral scholars, will illustrate the connections of mathematics to all areas of biology and will train a new generation of mathematical biologists. These efforts will be guided by the need to broaden participation by groups under-represented in the biological and mathematical sciences. The Center will develop a strong public outreach effort through a significant partnership and research collaboration with the National Park Service targeting visitors to the Great Smoky Mountains National Park.