U.S.-U.K. Planning Visit: Biochemical characterization of a candidate plant UV-B photoreceptor

美国-英国计划访问：候选植物 UV-B 光感受器的生化表征

• 批准号: 0836098
• 负责人: Ann Stapleton
• 金额: $ 1.03万
• 依托单位: University of North Carolina at Wilmington
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-15 至 2010-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0836098&HistoricalAwards=false
• 关键词: U.S.; U.K.; Planning; Visit; Biochemical

OISE 08-36098Ann StapletonUniversity of North Carolina - WilmingtonThis is a planning visit that provides support for the PI and one of her undergraduate students to travel to Cardiff University in the United Kingdom. The US principal investigator is Ann Stapleton from the University of North Carolina at Wilmington. The foreign collaborator is Gerlad Richter, an expert in photochemistry and biochemistry. The primary purpose of this visit is to establish a long-term collaborative partnership between the PI and Professor Richter. The focus of their research is on ultraviolet-B (UV-B) photoreceptors. No UV-B photoreceptor has been identified despite intensive effort by scientists world-wide. Mutant characterization of a candidate protein from Arabidopsis thaliana has provided intriguing mechanistic hypotheses for further biochemical analysis. Biochemical characterization of the first UV-B photoreceptor is key to understanding ozone depletion effects, such as prediction of the potential extent of trophic level alterations with increased UV-B. Together, the researchers will order a synthetic gene with optimized codon usage for E. coli expression.

OISE 08- 36098 Ann Stapleton北卡罗来纳州-威尔明顿大学这是一次计划访问，为PI和她的一名本科生前往英国的卡迪夫大学提供支持。 美国首席研究员是来自威尔明顿的北卡罗来纳州大学的安斯台普顿。 外国合作者是光化学和生物化学专家Gerlad Richter。这次访问的主要目的是建立PI和Richter教授之间的长期合作伙伴关系。他们的研究重点是紫外线-B（UV-B）光受体。 尽管全世界的科学家们付出了巨大的努力，但还没有发现UV-B光感受器。 拟南芥候选蛋白的突变体特征为进一步的生化分析提供了有趣的机制假说。 第一个UV-B光感受器的生物化学特性是理解臭氧消耗效应的关键，例如预测随着UV-B增加而发生的营养级变化的潜在程度。 总之，研究人员将订购一个具有优化密码子使用的合成基因。coli表达。