CRIF MU: Acquisition of a Multi-User GC-MS Instrument

该奖项是根据2009年《美国复苏和再投资法案》(Public Law 111-5)资助的。在化学研究仪器和设施多用户计划(CRIF：MU)的资助下，杰克逊州立大学(JSU)化学系将获得一台多用户GC-三重四极质谱计。该光谱仪将支持/加强下列研究活动：(1)四氢异喹啉衍生神经毒素的生物合成和代谢的立体化学；(2)多环芳烃的光化学反应机理；(3)烷氧基的大气化学；(4)11-脱氧呋喃-3及其合成类似物的合成；(5)光诱导核苷酸的核酸碱基激发、氧化和释放；以及(6)阴离子的超分子络合物。质谱仪(MS)是一种用于探测大量有机、生物有机和有机金属分子的内部结构细节和获得其分子组成的技术。这项研究也有望对环境产生积极影响。质谱法是发展最快、应用最广泛的分析仪器技术之一。正因为如此，对于这所HBCU的研究生和本科生来说，接触这项技术是很重要的。HBCU是三个拥有博士学位的大学之一。这款乐器将支持JSU的许多研究人员和学生，以及密歇根大学杰克逊分校的其他人。它将是教学和研究不可或缺的一部分。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Chemistry Research Instrumentation and Facilities Multiuser Program (CRIF:MU), the Chemistry Department at Jackson State University (JSU) will acquire a multi-user GC-triple quadrupole mass spectrometer. The spectrometer will enable/enhance research activities such as: (1) stereochemistry of biosynthesis and metabolism of tetrahydroisoquinoline-derived neurotoxins; (2) photochemical reaction mechanism of polycyclic aromatic hydrocarbons; (3) atmospheric chemistry of alkoxy radicals; (4) synthesis of 11-deoxyfistularin-3 and synthetic analogues; (5) light-induced nucleic acid base excitation, oxidation and release from nucleotides; and (6) supramolecular complexes of anions. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. This research is also expected to have a positive effect on the environment. MS is one of the fastest growing and most widely used analytical instrumentation techniques. Because of this, it is important for graduate and undergraduate students at this HBCU, one of three with a PhD program, to be exposed to the technique. This instrument will support many researchers and students at JSU and others in the metro Jackson MS area. It will be an integral part of teaching as well as research.