课题基金 / 基金详情

CAREER: Developing 1,2,3-triazole skeletons as novel chiral building blocks in asymmetric catalysis

CAREER: Developing 1,2,3-triazole skeletons as novel chiral building blocks in asymmetric catalysis
职业:开发 1,2,3-三唑骨架作为不对称催化中的新型手性结构单元
批准号:
0844602
负责人:
Xiaodong Shi
金额:
$55.0万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2009
资助国家:
美国
项目状态:
已结题
起止时间:
2009-09-01 至 2014-08-31

项目摘要

项目成果

Xiaodong Shi的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5). This project will work on the development of 1,2,3-triazole and its derivatives as novel ligands in promoting stereoselective functional group transformation for facile C-C and C-N bonds construction. While formation of 1,2,3-triazole through click-chemistry has been extensively applied in chemical and biological researches, most of the reported research focused on the application of click chemistry as biological compatible linkers and little progress has been made in the development of this interesting structural motif as new functional group in asymmetric catalysis. Studies to further elucidate the unique functionality of this motif and how it influences the metal catalyst reactivity will be undertaken. Combinatorial type screening of ligands with various transition metal cations will be carried out to identify new useful catalysts. Hypothesis driven studies of new asymmetric catalysis will be also performed. With this award, the Organic and Macromolecular Chemistry Program is supporting the research of Professor Xiaodong Shi of the Department of Chemistry at West Virginia University. Professor Shi's research efforts revolve around the development of new methods for the preparation of 1,2,3-triazole derivatives and asymmetric catalysis. Such chemistry will contribute to the fundamental understanding of ligand influence on catalyst reactivity and stereoselectivity. Successful development of the methodology will have an impact on synthesis in the pharmaceutical and chemical industries.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Achieving Challenging Synthesis Based on Triazole-Gold Catalysis
Developing Novel Triazole-Ruthenium Carbene Complexes (TA-Ru) for Challenging Olefin Metathesis Transformations
  • 批准号:
    2246822
  • 项目类别:
    Continuing Grant
  • 资助金额:
    $57.5万
  • 财政年份:
    2023
  • 负责人:
    Xiaodong Shi
  • 依托单位:
Achieving Challenging Synthesis Based on Triazole-Gold Catalysis
  • 批准号:
    2054180
  • 项目类别:
    Standard Grant
  • 资助金额:
    $32.95万
  • 财政年份:
    2021
  • 负责人:
    Xiaodong Shi
  • 依托单位:
Achieving Challenging Transformations with 1,2,3-Triazole Based Novel Metal Catalysts
  • 批准号:
    1665122
  • 项目类别:
    Standard Grant
  • 资助金额:
    $40.5万
  • 财政年份:
    2017
  • 负责人:
    Xiaodong Shi
  • 依托单位:
海外基金