CAREER: The integrative neurobiology of species recognition
职业:物种识别的综合神经生物学
基本信息
- 批准号:0845455
- 负责人:
- 金额:$ 70万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-06-15 至 2015-05-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).Species recognition is the process by which an animal distinguishes between members of its own species, conspecifics, from other closely related species, heterospecifics. Although species recognition has been well studied from ecological and evolutionary perspectives, there has been little work on its mechanisms. The investigators will study species recognition from these diverse perspectives using a novel mammalian model, Alston's singing mouse. The research aims in this project are 1) To examine interactions between two closely related singing mice, testing how individual and population-level interactions between species shape the responses of mice to heterospecific songs. 2) To examine the neural circuitry underlying species recognition. The investigators will measure whether Foxp2, a gene implicated in human language, is expressed in the same neurons that are activated by conspecific song. In the final research aim (3), the investigators will manipulate Foxp2 expression in both sensory and auditory structures. This will enable the investigators to understand how (and if) Foxp2 contributes to sensory and motivational processing of mouse song in a way that might inform our understanding of human speech. Because the mice are remarkably charismatic, the investigators will use the resulting data in educational materials targeting diverse groups of students. In the context of undergraduate education the research findings in combination with several new technologies (personal response systems based on text-messaging, online learning modules, and peer-reviewed writing software) will be used to develop innovative new course content. And lastly, the research data will be incorporated into a series of learning modules we are developing for use in Science Partners in Inquiry-based Collaborative Education, an outreach program that targets underperforming middle schools with high minority enrollments. Together this project promises to further our understanding of social behavior while streamlining the incorporation of new findings into the education of the general public.
该奖项是根据2009年美国复苏和再投资法案(公法111-5)资助的。物种识别是动物区分自己物种(同种)和其他密切相关物种(异种)的过程。虽然物种识别已经从生态学和进化的角度进行了很好的研究,但对其机制的研究很少。研究人员将使用一种新的哺乳动物模型,阿尔斯顿的歌唱老鼠,从这些不同的角度研究物种识别。本项目的研究目的是:1)研究两个密切相关的唱歌小鼠之间的相互作用,测试物种之间的个体和群体水平的相互作用如何塑造小鼠对异种歌曲的反应。2)去研究物种识别的神经回路。研究人员将测量Foxp 2(一种与人类语言有关的基因)是否在被同种歌曲激活的同一神经元中表达。在最终的研究目标(3)中,研究人员将操纵Foxp 2在感觉和听觉结构中的表达。这将使研究人员能够了解Foxp 2如何(以及是否)以一种可能告知我们对人类语言理解的方式对小鼠歌曲的感官和动机处理做出贡献。由于老鼠非常有魅力,研究人员将在针对不同学生群体的教育材料中使用由此产生的数据。在本科教育的背景下,研究结果与几种新技术(基于短信的个人响应系统,在线学习模块和同行评议的写作软件)相结合,将用于开发创新的新课程内容。最后,研究数据将被纳入我们正在开发的一系列学习模块中,用于基于探究的协作教育中的科学合作伙伴,这是一个针对少数民族入学率高的表现不佳的中学的推广计划。这个项目共同承诺,以进一步我们的社会行为的理解,同时简化新的发现纳入教育的一般公众。
项目成果
期刊论文数量(0)
专著数量(0)
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会议论文数量(0)
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David Reed其他文献
Development and application of computer-based prediction methods
计算机预测方法的开发与应用
- DOI:
10.1080/24748668.2005.11868334 - 发表时间:
2005 - 期刊:
- 影响因子:0
- 作者:
David Reed;P. O'Donoghue - 通讯作者:
P. O'Donoghue
Distributed agile software development for the SKA
SKA 的分布式敏捷软件开发
- DOI:
- 发表时间:
2012 - 期刊:
- 影响因子:0
- 作者:
A. Wicenec;R. Parsons;S. Kitaeff;K. Vinsen;Chen Wu;Paul R. Nelson;David Reed - 通讯作者:
David Reed
Modularity after the Crash
崩溃后的模块化
- DOI:
10.2139/ssrn.270292 - 发表时间:
2001 - 期刊:
- 影响因子:0
- 作者:
Carliss Y. Baldwin;Kim B. Clark;Masahiko Aoki;Richard Bergin;Wayne Collier;Mark Gaynor;Karim Lakhani;Alan MacCormack;Jan Rivkin;David Reed;J. Rusnak;Sonali Shah;Steve Spear;Don Sull;Kevin Sullivan - 通讯作者:
Kevin Sullivan
Rethinking John's Social Setting: Hidden Transcript, Anti-language, and the Negotiation of the Empire
反思约翰的社会背景:隐藏的文字记录、反语言和帝国的谈判
- DOI:
10.1177/01461079060360030201 - 发表时间:
2006 - 期刊:
- 影响因子:0.2
- 作者:
David Reed - 通讯作者:
David Reed
Poster 19: Compressive Optic Neuropathy in Low-Tension Glaucoma Suspect
- DOI:
10.1016/j.optm.2008.04.026 - 发表时间:
2008-06-01 - 期刊:
- 影响因子:
- 作者:
Kevin Talaga;David Reed - 通讯作者:
David Reed
David Reed的其他文献
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{{ truncateString('David Reed', 18)}}的其他基金
Parasitic lice as markers of modern and archaic human introgression
寄生虱子作为现代和古代人类基因渗入的标志
- 批准号:
1655600 - 财政年份:2017
- 资助金额:
$ 70万 - 项目类别:
Standard Grant
AGS-PRF: Observing and Diagnosing Mechanisms of Energy Balance in Temperate Freshwater Systems
AGS-PRF:温带淡水系统能量平衡的观测和诊断机制
- 批准号:
1430396 - 财政年份:2015
- 资助金额:
$ 70万 - 项目类别:
Fellowship Award
Disseration Research: Comparative genomics of mammal louse heritable symbionts
论文研究:哺乳动物虱子遗传共生体的比较基因组学
- 批准号:
1310824 - 财政年份:2013
- 资助金额:
$ 70万 - 项目类别:
Standard Grant
CAREER: Population genetics of Pediculus humanus using coalescent approaches with multi-locus data
职业:使用多位点数据的合并方法进行人类虱子的群体遗传学
- 批准号:
0845392 - 财政年份:2009
- 资助金额:
$ 70万 - 项目类别:
Standard Grant
Reconstructing the Evolutionary History of Bacterial Endosymbiosis in Obligate Blood-feeding Lice (Phthiraptera: Anoplura)
重建专性吸血虱子(Phthiraptera:Anoplura)细菌内共生的进化史
- 批准号:
0717165 - 财政年份:2007
- 资助金额:
$ 70万 - 项目类别:
Continuing Grant
Creating an Entrepreneurial Culture in a Rural Setting
在农村环境中创造创业文化
- 批准号:
0438528 - 财政年份:2006
- 资助金额:
$ 70万 - 项目类别:
Continuing Grant
BioCorder: A Biodiversity Inventory Tracking System
BioCorder:生物多样性库存跟踪系统
- 批准号:
0445712 - 财政年份:2005
- 资助金额:
$ 70万 - 项目类别:
Continuing Grant
Integrating Empirical Methods into the Computer Science Curriculum
将经验方法融入计算机科学课程
- 批准号:
0230950 - 财政年份:2003
- 资助金额:
$ 70万 - 项目类别:
Standard Grant
Implementing a Knowledge Management Infrastructure
实施知识管理基础设施
- 批准号:
0125380 - 财政年份:2001
- 资助金额:
$ 70万 - 项目类别:
Standard Grant
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