MRI: Acquisition of a Molecular Imaging Instrument for Dynamic Material and Biological Systems

MRI：获取用于动态材料和生物系统的分子成像仪器

• 批准号: 0922539
• 负责人: Stephen Boppart
• 金额: $ 177.09万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0922539&HistoricalAwards=false
• 关键词: MRI; Acquisition; Molecular; Imaging; Instrument

0922539Boppart"This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5)."The acquisition and use of this molecular imaging instrument will enable new research directions and educational opportunities and programs that will significantly contribute to the intellectual base of knowledge in these disparate but unified areas, and do so on national and international levels. The five research areas include (1) monitoring dynamic chemical reactions within advanced self-healing materials, (2) tracking nanoparticle biodistribution and visualizing their incorporation into the physiological processes of living organisms over time, (3) following the homing pathways of stem cells and their functional significance, (4) investigating metabolomics to understand the biological and physiological basis of nutrition, and (5) monitoring the dynamic three-dimensional distributions of materials, chemicals, and microbes in environmental samples. The acquisition of this molecular imaging instrument will not only enable the rapid expansion of existing research programs, but also provide the opportunity for new directions of investigation.

0922539 Boppart“该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。“这种分子成像仪器的获得和使用将使新的研究方向和教育机会和计划，将大大有助于知识的智力基础，在这些不同的，但统一的领域，并在国家和国际层面上这样做。这五个研究领域包括：（1）监测先进的自我修复材料中的动态化学反应，（2）跟踪纳米粒子的生物分布，并随着时间的推移将其纳入生物体的生理过程，（3）跟踪干细胞的归巢途径及其功能意义，（4）研究代谢组学，以了解营养的生物和生理基础，（5）监测环境样品中物质、化学物质和微生物的动态三维分布。获得这种分子成像仪器不仅可以快速扩展现有的研究计划，还可以为新的研究方向提供机会。