MRI: Acquisition of a Remotely Accessible 400 MHz Spectrometer

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。通过这项来自主要研究仪器（MRI）项目的奖励，来自霍普学院的Jeffrey B. Johnson和他的同事Moses Lee将获得一台400 MHz核磁共振光谱仪，用于支持包括过渡金属催化碳-碳键活化方法的机理阐明、用于前列腺癌可能应用的前药设计、有机光致变色的合成和分析等研究。用于发光电化学电池（LEC）的聚合物合成和表征，以及湖泊沉积物中磷酸盐的评估。该光谱仪还将通过网络基础设施为合作社区大学提供研究机会。核磁共振（NMR）波谱是化学家用来研究分子结构的最有力的工具之一。它用于识别未知物质，表征分子内原子的特定排列，以及研究溶液中分子之间相互作用的动力学。获得最先进的核磁共振光谱仪是必不可少的化学家谁正在进行前沿研究。这些核磁共振研究的结果将对合成有机/无机化学、生物化学、环境和能源研究产生影响。该仪器将成为教学和研究的一个组成部分。

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).With this award from the Major Research Instrumentation (MRI) program, Jeffrey B. Johnson and colleague Moses Lee from Hope College will acquire a 400 MHz NMR spectrometer to support research that includes mechanistic elucidation of transition metal-catalyzed carbon-carbon bond activation methodology, design of prodrugs for possible applications in prostate cancer, synthesis and analysis of organic photochromes, polymer synthesis and characterization for use in light emitting electrochemical cells (LEC), and assessment of phosphates in lake sediments. The spectrometer will also provide research opportunities at collaborating community colleges through cyber infrastructure.Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The results from these NMR studies will have an impact in synthetic organic/inorganic chemistry, biochemistry, environmental and energy research. This instrument will be an integral part of teaching as well as research.