SBIR Phase II: Water and Food Analysis by Non-Uniform Electroosmotic Flow

SBIR 第二阶段：通过非均匀电渗流分析水和食品

• 批准号: 0924350
• 负责人: Mark Peterman
• 金额: $ 50万
• 依托单位: OndaVia, Inc.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2013-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0924350&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Water; Food

This award is funded under the American Recovery and Reinvestment Act of 2009 (Public Law 111-5).This Small Business Innovation Research Phase II project will result in a prototype portable instrument for water quality analysis. The Phase I SBIR project was designed to show the feasibility of a new technique for separating uncharged polymers; this objective was met with remarkable quantitative accuracy, setting the stage for this Phase II prototype project. The underlying Phase I effort was based on stochastic mathematical models and molecular dynamics simulations through which the Labrador Research team discovered an electrokinetic approach for the separation of uncharged polymers. As efforts progressed, the power and potential of this approach as a generic separation technology became evident as our commercialization approach evolved into addressing the market need for water- and food-quality analysis technologies. This Phase II project will lead to a commercial prototype through iterative design improvements coupled with validation testing. The results obtained during Phase I and the anticipated Phase II results will set the stage for Phase III commercial participation by our financing partners and for rapid deployment of this proprietary chip technology in portable, hand-held analytical instruments. The world is running out of "quality" water for drinking and agricultural purposes. At the same time, public health agencies do not have the time, equipment, or resources to proactively check for hazardous chemicals in our drinking water, our water sources, or our food on a routine basis. Recent scares regarding melamine in baby food and pet food, bisphenol A in drinking water bottles, or perchlorate in ground water demonstrate the fragility of the water and food systems. Typical analysis requires collecting a sample in the field and shipping the sample to a test laboratory; water monitoring agencies depend upon these outsourced laboratories where transport and processing time can take days to produce results, wasting precious time when the health of a community is at stake. Existing portable tools can measure a few parts per million, whereas hazardous compounds are often regulated in the part per billion range. Handheld tools that measure a wide array of compounds at a parts-per-billion or better level would be a powerful, valuable, and necessary addition to the analysis toolbox.

该奖项是根据2009年美国复苏和再投资法案（公法111-5）资助的。这个小企业创新研究第二阶段项目将产生一个原型便携式水质分析仪器。第一阶段SBIR项目旨在展示一种分离不带电聚合物的新技术的可行性;这一目标以显著的定量准确性得到了满足，为第二阶段原型项目奠定了基础。第一阶段的基础工作是基于随机数学模型和分子动力学模拟，通过这些模型和模拟，拉布拉多研究小组发现了一种用于分离不带电聚合物的电动方法。随着努力的进展，这种方法作为一种通用分离技术的力量和潜力变得显而易见，因为我们的商业化方法逐渐发展成为满足市场对水和食品质量分析技术的需求。该第二阶段项目将通过迭代设计改进和验证测试实现商业原型。在第一阶段获得的结果和预期的第二阶段结果将为我们的融资合作伙伴的第三阶段商业参与以及在便携式手持分析仪器中快速部署这种专有芯片技术奠定基础。世界上用于饮用和农业的“优质”水正在耗尽。与此同时，公共卫生机构没有时间、设备或资源来主动检查我们的饮用水、水源或食品中的危险化学品。最近关于婴儿食品和宠物食品中的三聚氰胺、饮用水瓶中的双酚A或地下水中的高氯酸盐的恐慌表明了水和食品系统的脆弱性。典型的分析需要在现场收集样本并将样本运送到测试实验室;水监测机构依赖于这些外包实验室，运输和处理时间可能需要数天才能得出结果，当社区的健康受到威胁时，浪费了宝贵的时间。现有的便携式工具可以测量百万分之几，而危险化合物通常在十亿分之一的范围内。能够以十亿分之一或更高的水平测量各种化合物的手持式工具将是分析工具箱中强大、有价值和必要的补充。