EAGER: Collaborative Research: Integration of the Capillary Waveguide Biosensor (CWB) with the Environmental Sample Processor (ESP): Detection of microorga

EAGER：合作研究：毛细管波导生物传感器 (CWB) 与环境样品处理器 (ESP) 的集成：微生物检测

• 批准号: 0929356
• 负责人: Christopher Scholin
• 金额: $ 2.55万
• 依托单位: Monterey Bay Aquarium Research Institute
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0929356&HistoricalAwards=false
• 关键词: EAGER; Collaborative; Research; Integration; Capillary

The PI?s request EAGER funding to focus on validation of the coupled CWB-ESP instrument using field collected materials. This will not only allow the PI?s to overcome reviewer concerns, but will be a major step forward in preparing the CWB-ESP system for routine field deployment.. The main objectives include:1: Coupling the CWB to the ESP: the Microfluidic Block (MFB) interface2: Select and optimize hybridization and detection protocols3: Detection of targets in field-collected samples using model systemsBroader ImpactsThe proposed ESP-integrated CWB is potentially a major advance toward unattended, long term study of specific populations of the microbial community, with numerous potential applications beyond ecological research. During the course of this research, graduate, undergraduate and high school students will be involved directly and trained in the fundamentals of design and analysis of systems. The PI?s intend to engage diverse students and underserved minorities, by incorporating their research ideas and work into existing educational programs.

PI 请求 EAGER 资助，重点用于使用现场收集的材料验证耦合的 CWB-ESP 仪器。这不仅能让 PI 克服审稿人的担忧，而且将成为准备 CWB-ESP 系统进行常规现场部署的重要一步。主要目标包括：1：将 CWB 与 ESP 耦合：微流体块 (MFB) 接口 2：选择和优化杂交和检测协议 3：使用模型系统检测现场采集样本中的目标 更广泛的影响 ESP 集成的 CWB 可能是对微生物群落特定种群进行无人值守的长期研究的重大进步，在生态研究之外还有许多潜在的应用。在这项研究过程中，研究生、本科生和高中生将直接参与并接受系统设计和分析基础知识的培训。 PI 打算通过将他们的研究想法和工作纳入现有的教育计划来吸引不同的学生和服务不足的少数群体。