Role of Dopamine in LTP and Learning, Brandeis University, Spring 2010

多巴胺在 LTP 和学习中的作用，布兰迪斯大学，2010 年春季

• 批准号: 0935288
• 负责人: John Lisman
• 金额: $ 4.49万
• 依托单位: Brandeis University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-15 至 2011-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0935288&HistoricalAwards=false
• 关键词: Role; Dopamine; LTP; Learning; Brandeis

This is a proposal to host a workshop at Brandeis University on the role for learning of the neuromodulator dopamine--a key player in the brain's reward system. The format is to be a "discussion meeting" for an invited group of about 25 researchers, most of whom are working to understand how the neuromodulator dopamine affects synaptic plasticity in the brain, and thus plays a role in learning. Much of this work is new and unpublished. Only recently have investigators begun to realize that the role of dopamine in learning may be fundamental, so this is the best moment to bring those researchers together to discuss the effects of dopamine and the conditions under which it is released. This small gathering of active researchers should lead to more collaboration, and thus ensure that this new field will advance as rapidly and efficiently as possible.

这是一个在布兰迪斯大学举办一个关于神经调节剂多巴胺学习作用的研讨会的提议-多巴胺是大脑奖励系统的关键角色。会议的形式将是一个由25名研究人员组成的受邀小组的“讨论会”，其中大多数人都致力于了解神经调节剂多巴胺如何影响大脑中的突触可塑性，从而在学习中发挥作用。其中大部分是新的和未出版的。直到最近，研究人员才开始意识到多巴胺在学习中的作用可能是根本性的，所以这是将这些研究人员聚集在一起讨论多巴胺的作用及其释放条件的最佳时刻。 这个活跃的研究人员的小聚会应该会带来更多的合作，从而确保这个新领域尽可能快速有效地发展。