SBIR Phase I: Phage control of filamentous bacteria - A novel focused antimicrobial approach to counter microbial problems in municipal wastewater systems

SBIR 第一阶段：丝状细菌的噬菌体控制 - 一种解决城市废水系统中微生物问题的新型集中抗菌方法

• 批准号: 0945913
• 负责人: Neil Summer
• 金额: --
• 依托单位: Phage Biocontrol Research, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2010-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0945913&HistoricalAwards=false
• 关键词: SBIR; Phase; Phage; control; filamentous

This SBIR Phase I project will develop a phage technology to remediate and control the foam-causing microorganisms at wastewater treatment plants. The research will include isolation of problematic foaming Nocardia species, isolation of phage capable of killing foaming Nocardia, and evaluation of phage clearing of Nocardia in batch culture test systems. This is an important issue in wastewater treatment and the concept of using phage for foam control in waste water systems is innovative.The broader/commercial impacts of the proposed project will be the potential applications of the proposed technology. Activated sludge wastewater treatment processes are common. Problematic foaming caused by excessive microbial growth occurs if the operation conditions are not optimized. The project will allow development of an innovative solution and if successful, should have significant commercial value.

该SBIR第一阶段项目将开发噬菌体技术，以修复和控制污水处理厂的泡沫微生物。 该研究将包括分离有问题的发泡诺卡氏菌物种，分离能够杀死发泡诺卡氏菌的噬菌体，并评估噬菌体清除诺卡氏菌在分批培养测试系统。这是废水处理中的一个重要问题，利用噬菌体控制废水系统中的泡沫的概念是创新的。拟议项目的更广泛/商业影响将是拟议技术的潜在应用。 活性污泥废水处理工艺是常见的。 如果操作条件未优化，则会发生由微生物过度生长引起的问题性起泡。 该项目将允许开发一种创新的解决方案，如果成功，将具有重大的商业价值。