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Reconciling gene trees: Deciphering the source and extent of genealogical discordance

Reconciling gene trees: Deciphering the source and extent of genealogical discordance
协调基因树:破译家谱不一致的根源和程度
批准号:
0949121
负责人:
Cecile Ane
金额:
$50.54万
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-06-01 至 2014-05-31

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中文摘要
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英文摘要
The discordant signal obtained from analysis of different genes has raised new challenges for biologists. When contradictory evolutionary relationships are detected across different parts of the genome, it is difficult to recover and describe the history of a group of species. But this discordance among genes has also raised new opportunities: hybridization, gene flow, and other biological processes each leave their own signature in the pattern of gene tree variability. The goal of this project is to estimate the discordance between gene trees and the biological processes that have affected species and populations. An interdisciplinary team of statisticians, biologists and computer scientists will develop new and robust statistical methods for analysis of genes and species relationships. The tools developed through this project will be implemented in a user-friendly program so that all phylogeneticists can utilize them. Software will be freely distributed to facilitate the utilization of these tools for the study of other groups of species. Undergraduate and graduate students will be trained at the interface between biology, statistics and computer science. Insights from this research will enhance educational modules in evolutionary theory at the undergraduate level and at K-12 teacher workshops.
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