CAREER: Nanoelectrochemical systems on silicon

智力优势：拟议的职业研究的主要目标是通过将微电子学和电化学结合起来实现纳米电化学系统，以实现低成本、高通量的台式纳米制造。PI提出了一种高度非常规但功能强大的候选方案来实现这种纳米电化学设备？采用自上而下制造的硅互补金属氧化物半导体芯片作为可控纳米加工的功能衬底。这一新的范例将CMOS技术的作用从传统的计算、信号处理和通信领域扩展到定向纳米组装和纳米制造。这项研究将开发两种方法：(1)用于纳米组装的CMOS：电场操纵和已合成纳米结构的组装；(2)用于纳米制造的CMOS：直接在CMOS上控制不同类型的纳米线的电化学生长。内置集成电路将促进组装和生长的实时反馈控制，并可作为传感的前端电路重复使用。该研究为多种纳米材料在同一硅片上的异质集成提供了一条直接的途径。作为概念的证明，PI计划实现用于生物分析的纳米电化学传感器，主要是检测神经递质，以及对实际样品中痕量重金属离子的环境传感。广泛影响：如果研究成功，将通过在化学和生物传感、高速电子以及能源产生和储存设备领域的创新和产品开发，产生巨大的经济和社会影响。作为综合教育和外展计划的一部分，PI将实施四项主要举措：(I)本科课程中以项目为基础的学习举措(Ii)自下而上的纳米制造研究生课程，(Iii)面向本科生的跨学科研究经验，以及(Iv)面向公众的基于网络的单元。少数群体和代表不足群体的参与计划包括：(1)为塔夫茨大学和西蒙斯学院的女学生提供暑期和学期的研究机会，这是一个全由女性组成的本科院校；(2)通过塔夫茨大学STEM多样性中心宣传，为代表不足群体提供暑期实习机会；(3)通过学生教师指导方案和在梅德福德和马尔登地区当地高中举行的研讨会，向社区开展外联活动。

Intellectual Merits: The main objective of the proposed career research is the realization of nanoelectrochemical systems through a marriage of microelectronics and electrochemistry for low-cost, high-throughput bench-top nanofabrication. The PI proposes a highly unconventional yet powerful candidate to realize such nanoelectrochemical devices ? that of top-down fabricated silicon CMOS (Complementary Metal Oxide Semiconductor) die as functional substrate for controlled nanofabrication. This new paradigm extends the role of CMOS technology beyond conventional areas of computation, signal processing and communication towards directed nanoassembly and nanofabrication. The proposed research will develop two approaches: (1) CMOS for Nanoassembly: Electric field manipulation and assembly of already synthesized nanostructures and (2) CMOS for Nanofabrication: Controlled electrochemical growth of different types of nanowires directly on CMOS. Built-in integrated circuits will facilitate real-time feedback control for assembly and growth, and can be reused as front-end circuits for sensing. The research provides a direct path for heterogeneous integration of multiple nanomaterials on same silicon chip. As a proof of concept, the PI plans to implement a nanoelectrochemical sensor for bioanalysis, primarily detection of neurotransmitters, and environmental sensing of trace heavy metal ions in actual samples.Broader impacts: The research, if successful, will have tremendous economic and societal impact through innovation and product development in areas of chemical and biological sensing, high-speed electronics, and devices for energy generation and storage. The PI will implement four key initiatives as part of the integrated education and outreach plan: (i) Project-based learning initiatives in undergraduate courses (ii) Graduate level course on Bottom-up nanomanufacturing, (iii) Interdisciplinary research experience for undergraduates, and (iv) Web based modules for public audience. Plans for participation of minorities and under-represented groupa include: (i) Summer and semester long research opportunities for women students from Tufts University and Simmons College, an all-women undergraduate institution (ii) Summer internship opportunities for under-represented groups advertised through the Center for STEM Diversity at Tufts University and (iii) K-12 and community outreach through student teacher mentorship programs and seminars at local high-schools in the Medford and Malden areas.