REU Site: Summer Research in Chemistry at Boise State University for First Year Undergraduates

REU 网站：博伊西州立大学一年级本科生暑期化学研究

• 批准号: 1005159
• 负责人: Don Warner
• 金额: $ 32.5万
• 依托单位: Boise State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2014-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1005159&HistoricalAwards=false
• 关键词: REU; Site; Summer; Research; Chemistry

This award from the Division of Chemistry (CHE) and the Division of Biological Infrastructure (DBI) supports a Research Experience for Undergraduates (REU) site led by Don L. Warner at Boise State University for the summers of 2010-2012. The site will support ten students per summer in a ten week program. The research projects focus on research in areas that span areas of chemistry and biology. Sample projects include: (1) a study of the ways in which the coordinating metal alters the functionality of the peptide deformylase enzyme; (2) the study of the DNA-binding properties of synthetic aziridinomitosenes; (3) the study of the substrate and inhibitor recognition by human carbonyl reductase; (4) the study of quorum sensing in mutants of methicillin resistant staphylococcus aureus; (5) the colorimetric detection of DNA with oligonucleotide-functionalized colloidal gold nanoparticles; (6) the calculation of the structure and binding of conotoxin ligands with the acetylcholine-binding protein of A. californica; and (7) the study of the binding of actinides with dithiophosphonic acid ligands. Besides being exposed to compelling research, the students participating in this program will participate in site visits, social activities, and professional development activities -- including sessions on peer mentoring (for returning students) and ethics in scientific research. The site will recruit from first year students from regional 2-year and 4-year colleges with little research infrastructure. Many of the targeted students are first-generation college students and members of other groups underrepresented in the sciences.Young scientists need exposure to modern research methods and tools as part of their training. This REU site aims to provide practical, hands-on research training to a significant number of students who might not have this opportunity at their home institution. The interdisciplinary projects that the students will work on while at Boise State University, are excellent examples of the kinds of cross-disciplinary work that is becoming more and more typical of the most fruitful avenues for modern laboratory research. Students participating in research at this site will be well-prepared for graduate school, and eventual employment as part of the country's technical workforce.

该奖项由化学部（CHE）和生物基础设施部（DBI）颁发，支持博伊西州立大学2010-2012年夏季由Don L. Warner领导的本科生研究经验（REU）项目。该网站每年夏天将为10名学生提供为期10周的培训。研究项目侧重于跨越化学和生物学领域的研究。样本项目包括：(1)研究配位金属改变肽去甲酰基酶功能的方式；(2)合成aziridinomitosenes的dna结合特性研究；(3)人羰基还原酶对底物和抑制剂的识别研究；(4)耐甲氧西林金黄色葡萄球菌突变体群体感应的研究；(5)用寡核苷酸功能化胶体金纳米颗粒比色法检测DNA；(6)加利福尼亚加利福尼亚加利福尼亚加利福尼亚螺毒素配体与乙酰胆碱结合蛋白的结构及结合计算；(7)锕系元素与二硫代膦酸配体结合的研究。除了接触到引人注目的研究之外，参加该项目的学生还将参加实地考察、社会活动和专业发展活动——包括同侪指导（针对归国学生）和科学研究伦理的会议。该网站将从几乎没有研究基础设施的地区两年制和四年制大学招收一年级学生。许多目标学生是第一代大学生和其他在科学领域代表性不足的群体的成员。作为培训的一部分，年轻科学家需要接触现代研究方法和工具。这个REU网站旨在为大量学生提供实用的，动手的研究培训，这些学生可能在他们的家庭机构没有这种机会。学生们将在博伊西州立大学进行的跨学科项目是跨学科工作的优秀范例，这些跨学科工作越来越成为现代实验室研究最富有成果的典型途径。在这里参与研究的学生将为读研做好充分准备，并最终成为国家技术劳动力的一部分。