REU Site: Summer Research in Chemistry at Boise State University for First Year Undergraduates

化学部（CHE）和生物基础设施部（DBI）的这一奖项支持由Don L. 2010-2012年夏天，华纳在博伊西州立大学。 该网站将支持10名学生每年夏天在一个为期十周的计划。 研究项目侧重于跨化学和生物学领域的研究。 示例项目包括：（1）研究配位金属改变肽脱甲酰基酶功能的方式;（2）研究合成的氮杂环丙啶并米托烯的DNA结合特性;（3）研究人羰基还原酶对底物和抑制剂的识别;（4）研究耐甲氧西林金黄色葡萄球菌突变体的群体感应;（6）芋螺毒素配体的结构计算及其与乙酰胆碱结合蛋白的结合。calfornica;（7）锕系元素与二硫代膦酸配体结合的研究。 除了接触到令人信服的研究，参加该计划的学生将参加实地考察，社会活动和专业发展活动-包括同行指导（为归国学生）和科学研究道德的会议。 该网站将从一年级的学生从区域2年制和4年制大学几乎没有研究基础设施招募。 许多目标学生是第一代大学生和其他在科学领域代表性不足的群体的成员。年轻科学家需要接触现代研究方法和工具，作为他们培训的一部分。 这个REU网站的目的是提供实用的，动手研究培训的学生谁可能没有这个机会在他们的家机构的显着数量。 学生将在博伊西州立大学工作的跨学科项目，是跨学科工作的典范，这种跨学科工作越来越成为现代实验室研究最富有成效的途径的典型。 在这个网站上参与研究的学生将为研究生院做好充分的准备，并最终成为该国技术劳动力的一部分。

This award from the Division of Chemistry (CHE) and the Division of Biological Infrastructure (DBI) supports a Research Experience for Undergraduates (REU) site led by Don L. Warner at Boise State University for the summers of 2010-2012. The site will support ten students per summer in a ten week program. The research projects focus on research in areas that span areas of chemistry and biology. Sample projects include: (1) a study of the ways in which the coordinating metal alters the functionality of the peptide deformylase enzyme; (2) the study of the DNA-binding properties of synthetic aziridinomitosenes; (3) the study of the substrate and inhibitor recognition by human carbonyl reductase; (4) the study of quorum sensing in mutants of methicillin resistant staphylococcus aureus; (5) the colorimetric detection of DNA with oligonucleotide-functionalized colloidal gold nanoparticles; (6) the calculation of the structure and binding of conotoxin ligands with the acetylcholine-binding protein of A. californica; and (7) the study of the binding of actinides with dithiophosphonic acid ligands. Besides being exposed to compelling research, the students participating in this program will participate in site visits, social activities, and professional development activities -- including sessions on peer mentoring (for returning students) and ethics in scientific research. The site will recruit from first year students from regional 2-year and 4-year colleges with little research infrastructure. Many of the targeted students are first-generation college students and members of other groups underrepresented in the sciences.Young scientists need exposure to modern research methods and tools as part of their training. This REU site aims to provide practical, hands-on research training to a significant number of students who might not have this opportunity at their home institution. The interdisciplinary projects that the students will work on while at Boise State University, are excellent examples of the kinds of cross-disciplinary work that is becoming more and more typical of the most fruitful avenues for modern laboratory research. Students participating in research at this site will be well-prepared for graduate school, and eventual employment as part of the country's technical workforce.