Collaborative Research: Assessing the Effect of Environmental Stressors on Invertebrate Innate Immunity using a Coral Pathosystem

合作研究:利用珊瑚病理系统评估环境压力源对无脊椎动物先天免疫的影响

基本信息

  • 批准号:
    1017458
  • 负责人:
  • 金额:
    $ 40.95万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-09-01 至 2014-08-31
  • 项目状态:
    已结题

项目摘要

Mydlarz, Laura IOS-1017458LiT: Collaborative Research: Assessing the effect of environmental stressors on invertebrate innate immunity using a coral pathosystemThe abundance of reef-building corals has declined dramatically over the last decades. The main causes of coral loss are related to ocean warming, nutrient pollution and disease outbreaks, all resulting from anthropogenic-induced climate change. Observations indicate that number and prevalence of coral diseases have increased over the last two decades and new epizootics nearly every year suggest that environmental stressors drive or exacerbate coral disease. This project will examine coral resistance to pathogens and variation in innate immunity, as well as quantify the effects of ocean warming and nutrient pollution on the effectiveness of coral immune responses. The project will focus on the Montastraea faveolata Yellow Band Disease (YBD) system. The genus Montastraea is one of the most important groups of corals of modern western Atlantic coral reefs, however, Montastraea spp. populations have declined dramatically mainly due to bleaching and disease. Using assays for cellular and cell-free processes in coral immunity, the PIs will examine the variability in disease resistance in naturally infected corals, the reaction time and recovery time from temperature stress and how the combination of stressors influence coral immunity in the presence of YBD pathogens. This project will also train undergraduates and graduate students at multiple universities, and promote exchange between four universities. Funding will support a novel service-learning project. Undergraduate students from an upper-level marine biology course will prepare and execute a lesson plan for junior high school students based on concepts from their course and this project. One of the investigators on this project will collaborate with professional educators and outreach specialists at a Planetarium and a public-oriented Science Center to develop an interactive museum display and K-4 summer camp programs.
劳拉?米德拉兹 IOS-1017458 LiT:合作研究:使用珊瑚病理系统评估环境压力对无脊椎动物先天免疫的影响在过去的几十年里,造礁珊瑚的丰度急剧下降。珊瑚丧失的主要原因与海洋变暖、营养物污染和疾病爆发有关,所有这些都是由气候变化引起的。 观察表明,过去二十年来,珊瑚疾病的数量和流行率有所增加,几乎每年都有新的动物流行病发生,这表明环境压力驱动或加剧了珊瑚疾病。 该项目将研究珊瑚对病原体的抵抗力和先天免疫的变化,并量化海洋变暖和营养污染对珊瑚免疫反应有效性的影响。 该项目将侧重于Montastraea faveolata黄带病(YBD)系统。 Montastraea属是现代西大西洋珊瑚礁中最重要的珊瑚群之一,然而,Montastraea spp.主要由于白化和疾病,种群数量急剧下降。利用珊瑚免疫中的细胞和无细胞过程的分析,PI将研究自然感染的珊瑚的抗病能力的变化,温度压力的反应时间和恢复时间,以及在YBD病原体存在的情况下,压力因素的组合如何影响珊瑚的免疫力。 该项目还将培训多所大学的本科生和研究生,并促进四所大学之间的交流。 资金将支持一个新的服务学习项目。 来自高级海洋生物学课程的本科生将根据他们课程和本项目的概念为初中生准备和执行课程计划。 该项目的一名调查人员将与天文馆和面向公众的科学中心的专业教育工作者和外展专家合作,开发互动式博物馆展示和K-4夏令营项目。

项目成果

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Laura Mydlarz其他文献

Laura Mydlarz的其他文献

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{{ truncateString('Laura Mydlarz', 18)}}的其他基金

RAPID: Collaborative Research: Predicting the Spread of Multi-Species Coral Disease Using Species Immune Traits
RAPID:合作研究:利用物种免疫特征预测多物种珊瑚疾病的传播
  • 批准号:
    1928771
  • 财政年份:
    2019
  • 资助金额:
    $ 40.95万
  • 项目类别:
    Standard Grant
Meeting: The -omics of chemical interactions in simple extant animals ; Society for Integrative and Comparative Biology, Tampa, Florida, January 3-7, 2019
会议:简单现存动物化学相互作用的组学;
  • 批准号:
    1831860
  • 财政年份:
    2018
  • 资助金额:
    $ 40.95万
  • 项目类别:
    Standard Grant
Immunity to Community: Can Quantifying Immune Traits Inform Reef Community Structure?
群落免疫:量化免疫特征能否为珊瑚礁群落结构提供信息?
  • 批准号:
    1712134
  • 财政年份:
    2017
  • 资助金额:
    $ 40.95万
  • 项目类别:
    Standard Grant
COLLABORATIVE RESEARCH: Influence of Temperature and Acidification on the Dynamics of Coral Co-Infection and Resistance
合作研究:温度和酸化对珊瑚共同感染和抵抗力动态的影响
  • 批准号:
    0849799
  • 财政年份:
    2009
  • 资助金额:
    $ 40.95万
  • 项目类别:
    Standard Grant

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