Meeting: The -omics of chemical interactions in simple extant animals ; Society for Integrative and Comparative Biology, Tampa, Florida, January 3-7, 2019

会议:简单现存动物化学相互作用的组学;

基本信息

  • 批准号:
    1831860
  • 负责人:
  • 金额:
    $ 1.47万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2018
  • 资助国家:
    美国
  • 起止时间:
    2018-09-15 至 2019-08-31
  • 项目状态:
    已结题

项目摘要

This symposium will bring together researchers from diverse backgrounds, fields, institutes and career stages to engage with each other and with conference attendees. The topic of the symposia is "Chemical responses to the biotic and abiotic environment by early diverging metazoans revealed in the post-genomic age." The interaction of speakers and topics will stimulate new insights, hypotheses and collaborations. In turn, these will enhance progress in the field. The symposium will have a SICB-hosted website that will serve as a repository for information on all aspects of the researchers and their work. A minimum of 11 peer-reviewed publications, along with supplementary data, will be published in the journal Integrative and Comparative Biology as major products of the symposium. The symposium has a strong commitment to advancing the careers of women in science and employment in higher education and research, as 60% of the speakers are women. A complementary session will provide a platform for early career researchers to disseminate research related to the theme of the symposium. The symposium will lead to development of resources that will be available to students and researchers for many years to come. Extant early-diverging metazoans (Cnidaria, Ctenophora, Placozoa, and Porifera) have survived in a changing and increasingly complex world, and -omics data are providing novel insights on a diversity of peptides and small molecules that these animals deploy. It is clear that surprisingly sophisticated gene repertoires enable basal metazoans to encode many of the signaling, sensory, defensive and offensive capacities associated with "higher" animals. It is now timely to consider how omics methods can be used to resolve how environmental and chemical queues shape phenotypes among the basal metazoans by focusing on how these simple animals have evolved a diversity of chemical responses to environmental stimuli. The aim of this symposium is to develop a post-genomic view on the form, functions and origins of compounds that are biosynthesized in early diverging metazoans in response to environmental cues. Invited speakers will contribute talks in three general areas: 1) the molecular basis of perception, 2) chemicals deployed to deal with the biotic and abiotic environment, and 3) the molecular cross-talk that characterizes intimate interactions of hosts, parasites and symbionts. Specific topics that will be considered include: toxin diversity, life styles and co-option of chemicals, immune molecules, the chemistry of cellular reception, and sensory complexity in simple animals. The topics of this symposium and resulting interactions of speakers will contribute to a growing picture of comparative functional biochemistry, revealing how chemical mediators have enabled persistence and diversification of simple animals that lack sophisticated morphologies, anatomies and behaviors over geological time.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
本次研讨会将汇集来自不同背景,领域,机构和职业阶段的研究人员,相互交流,并与与会者。研讨会的主题是“后基因组时代揭示的早期分化后生动物对生物和非生物环境的化学反应”。“演讲者和主题的互动将激发新的见解,假设和合作。反过来,这将促进该领域的进展。专题讨论会将有一个SICB主办的网站,作为关于研究人员及其工作的所有方面的信息库。至少有11篇同行评审的出版物,沿着补充数据,将作为专题讨论会的主要成果发表在《综合与比较生物学》杂志上。研讨会有一个坚定的承诺,以促进妇女在科学和就业的高等教育和研究的职业生涯,因为60%的发言者是妇女。一个补充会议将为早期职业研究人员提供一个平台,以传播与专题讨论会主题有关的研究。研讨会将导致资源的开发,将提供给学生和研究人员在未来许多年。现存的早期分化后生动物(刺胞动物,栉水母,Placozoa和多孔动物)在不断变化和日益复杂的世界中生存下来,组学数据提供了新的见解,这些动物部署的肽和小分子的多样性。很明显,令人惊讶的复杂基因库使基础后生动物能够编码许多与“高等”动物相关的信号,感觉,防御和攻击能力。现在是时候考虑如何组学方法可以用来解决如何环境和化学队列形状表型之间的基础后生动物,专注于这些简单的动物如何进化的多样性的化学反应,环境刺激。本次研讨会的目的是发展一个后基因组的形式,功能和起源的化合物,生物合成的早期分化后生动物在响应环境线索。受邀演讲者将在三个一般领域进行演讲:1)感知的分子基础,2)用于处理生物和非生物环境的化学品,以及3)表征宿主,寄生虫和共生体之间密切相互作用的分子串扰。将考虑的具体主题包括:毒素的多样性,生活方式和化学品的选择,免疫分子,细胞接收的化学,以及简单动物的感觉复杂性。本次研讨会的主题和演讲者的互动将有助于比较功能生物化学的不断发展,揭示化学介质如何使缺乏复杂形态的简单动物得以持久和多样化,该奖项反映了NSF的法定使命,并被认为是值得通过使用基金会的智力价值和更广泛的评估支持。影响审查标准。

项目成果

期刊论文数量(11)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Light-induced stress as a primary evolutionary driver of eye origins
光诱导的压力是眼睛起源的主要进化驱动力
  • DOI:
    10.1093/icb/icz064
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    2.6
  • 作者:
    Swafford, Andrew J. M.;Oakley, Todd H.
  • 通讯作者:
    Oakley, Todd H.
Chemical Ecology of Marine Sponges: New Opportunities through "-Omics"
  • DOI:
    10.1093/icb/icz014
  • 发表时间:
    2019-10-01
  • 期刊:
  • 影响因子:
    2.6
  • 作者:
    Paul, Valerie J.;Freeman, Christopher J.;Agarwal, Vinayak
  • 通讯作者:
    Agarwal, Vinayak
Combing Transcriptomes for Secrets of Deep-Sea Survival: Environmental Diversity Drives Patterns of Protein Evolution
  • DOI:
    10.1093/icb/icz063
  • 发表时间:
    2019-05
  • 期刊:
  • 影响因子:
    2.6
  • 作者:
    Jacob R Winnikoff;Jacob R Winnikoff;Warren R. Francis;E. V. Thuesen;S. Haddock;S. Haddock
  • 通讯作者:
    Jacob R Winnikoff;Jacob R Winnikoff;Warren R. Francis;E. V. Thuesen;S. Haddock;S. Haddock
Still Enigmatic: Innate Immunity in the Ctenophore Mnemiopsis leidyi
仍然是个谜:栉水母 Mnemiopsis leidyi 的先天免疫
  • DOI:
    10.1093/icb/icz116
  • 发表时间:
    2019
  • 期刊:
  • 影响因子:
    2.6
  • 作者:
    Traylor-Knowles, Nikki;Vandepas, Lauren E;Browne, William E
  • 通讯作者:
    Browne, William E
Sponge Behavior and the Chemical Basis of Responses: A Post-Genomic View
  • DOI:
    10.1093/icb/icz122
  • 发表时间:
    2019-10-01
  • 期刊:
  • 影响因子:
    2.6
  • 作者:
    Leys, Sally P.;Mah, Jasmine L.;Kahn, Amanda S.
  • 通讯作者:
    Kahn, Amanda S.
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Laura Mydlarz其他文献

Laura Mydlarz的其他文献

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{{ truncateString('Laura Mydlarz', 18)}}的其他基金

RAPID: Collaborative Research: Predicting the Spread of Multi-Species Coral Disease Using Species Immune Traits
RAPID:合作研究:利用物种免疫特征预测多物种珊瑚疾病的传播
  • 批准号:
    1928771
  • 财政年份:
    2019
  • 资助金额:
    $ 1.47万
  • 项目类别:
    Standard Grant
Immunity to Community: Can Quantifying Immune Traits Inform Reef Community Structure?
群落免疫:量化免疫特征能否为珊瑚礁群落结构提供信息?
  • 批准号:
    1712134
  • 财政年份:
    2017
  • 资助金额:
    $ 1.47万
  • 项目类别:
    Standard Grant
Collaborative Research: Assessing the Effect of Environmental Stressors on Invertebrate Innate Immunity using a Coral Pathosystem
合作研究:利用珊瑚病理系统评估环境压力源对无脊椎动物先天免疫的影响
  • 批准号:
    1017458
  • 财政年份:
    2010
  • 资助金额:
    $ 1.47万
  • 项目类别:
    Standard Grant
COLLABORATIVE RESEARCH: Influence of Temperature and Acidification on the Dynamics of Coral Co-Infection and Resistance
合作研究:温度和酸化对珊瑚共同感染和抵抗力动态的影响
  • 批准号:
    0849799
  • 财政年份:
    2009
  • 资助金额:
    $ 1.47万
  • 项目类别:
    Standard Grant

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评估产前邻苯二甲酸盐暴露如何扰乱胎盘转录调节并导致妊娠长度的变化
  • 批准号:
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