The material basis of function in the brain: Connections to philosophy of biology and phenomenology

大脑功能的物质基础:与生物学哲学和现象学的联系

基本信息

  • 批准号:
    1026632
  • 负责人:
  • 金额:
    $ 5.95万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2010
  • 资助国家:
    美国
  • 起止时间:
    2010-09-15 至 2012-08-31
  • 项目状态:
    已结题

项目摘要

IntroductionThis project brings together two distinct perspectives on the mind and the brain, one based in neuroscience and the other in philosophy. The Co-PI (a neuroscientist) will bridge these perspectives by exploring connections between neuroscientific work on cellular mechanisms in the brain and work in phenomenology on the experience of the body in mind-like activities; the PI will do so in collaboration with the PI, a philosopher. The proposed project will serve to articulate and expand the conceptual underpinnings of neuroscience to fit new data using insights from phenomenology.Intellectual meritThree central themes of neuroscience are at issue in this project. They are the following. The central purpose of the brain is to process information, neurons are the key functional constituents of the brain, and information processing is performed by patterns of neuron activation. The discovery of an active role for astrocytes and other non-neuronal elements in shaping the brain's activities is straining the central themes of neuroscience indicated above since these discoveries suggest that information processing may not be so easily divorced from other material elements such as the surrounding astrocytes and blood flow, the roles of particular molecules, or cellular processes within the neuron that make it possible. The Co-PI will draw parallels to similar debates in the nature of biological information, where it has been argued that genetic information is an oversimplification that is meaningless except in the particular cellular context in which it appears. The Co-PI will do so by exploring ways in which the phenomenologist's notion of embodiment may apply not just at the level of an individual organism, but at the cellular and cell-assembly level in the brain as well. Phenomenologist has long argued that mental activities like perception must also be intensely and intrinsically physical and bound to our bodies and engagement with their physical environments.Potential Broader impactsThe project promises to improve communication between the field of neuroscience and philosophy. It will provide an expanded definition of the core endeavor of neuroscience, and it will also provide an articulation of the advantages and dangers of a functionalist or computational approach to the brain that abstracts away the biological details of functions. The goal is to enhance awareness of these implications among scientists and philosophers, as well as sponsors of large new projects that depend on the computational approach, such as the Human Connectome Initiative of NIH.
这个项目汇集了两个关于头脑和大脑的截然不同的观点,一个基于神经科学,另一个基于哲学。Co-Pi(一位神经学家)将通过探索神经科学工作中大脑中的细胞机制与现象学中关于身体在类似头脑的活动中的体验之间的联系来弥合这些观点;PI将与哲学家Pi合作做到这一点。拟议的项目将用于阐明和扩展神经科学的概念基础,以适应新的数据,使用现象学的见解。智力价值神经科学的三个中心主题在这个项目中存在争议。它们如下所示。大脑的中心目的是处理信息,神经元是大脑的关键功能成分,信息处理是通过神经元激活的模式进行的。星形胶质细胞和其他非神经性元素在塑造大脑活动中的积极作用的发现,正在紧张上述神经科学的中心主题,因为这些发现表明,信息处理可能不那么容易脱离其他物质元素,如周围的星形胶质细胞和血液流动,特定分子的作用,或神经元内使其成为可能的细胞过程。CoPI将与生物信息性质的类似辩论相提并论,后者认为遗传信息是一种过度简单化,除非在它出现的特定细胞环境中,否则是没有意义的。Co-Pi将通过探索现象学家的具体化概念不仅可以应用于单个有机体的层面,而且也可以应用于大脑中的细胞和细胞组装层面来做到这一点。现象学家长期以来一直认为,像感知这样的心理活动也必须是强烈和内在的物理活动,并与我们的身体和他们的物理环境相联系。潜在的更广泛的影响该项目承诺改善神经科学和哲学领域之间的沟通。它将为神经科学的核心工作提供一个扩展的定义,它还将提供对大脑的功能主义或计算方法的优势和危险的阐述,这种方法抽象出功能的生物学细节。其目标是提高科学家和哲学家以及依赖于计算方法的大型新项目的发起人对这些影响的认识,例如美国国立卫生研究院的人类连接组倡议。

项目成果

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Sean Kelly其他文献

Modeling Classroom Discourse: Do Models of Predicting Dialogic Instruction Properties Generalize across Populations?
课堂话语建模:预测对话教学属性的模型是否可以在人群中推广?
  • DOI:
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Borhan Samei;A. Olney;Sean Kelly;M. Nystrand;S. D’Mello;Nathaniel Blanchard;A. Graesser
  • 通讯作者:
    A. Graesser
Specular highlights as a guide to perceptual content
镜面高光作为感知内容的指南
  • DOI:
  • 发表时间:
    2008
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Alva Noë;Sean Kelly;Bruce W. Brower;A. Clark
  • 通讯作者:
    A. Clark
AC 2010-622: PREDICTION OF SOPHOMORE RETENTION
AC 2010-622:大二学生保留率预测
  • DOI:
  • 发表时间:
    2010
  • 期刊:
  • 影响因子:
    0
  • 作者:
    C. Pieronek;Kerry Meyers;Sean Kelly;L. H. Mcwilliams
  • 通讯作者:
    L. H. Mcwilliams
Hydrographic maintenance of deep anoxia in a tidally influenced saline lagoon
受潮汐影响的咸水湖深度缺氧的水文维持
  • DOI:
    10.1071/mf17199
  • 发表时间:
    2017
  • 期刊:
  • 影响因子:
    1.8
  • 作者:
    Sean Kelly;E. Eyto;M. Dillane;R. Poole;G. Brett;M. White
  • 通讯作者:
    M. White
Autoerotic nonlethal filmed hangings: a case series and comments on the estimation of the time to irreversibility in hanging.
自体性非致命性绞刑:一系列案例和对绞刑不可逆转时间估计的评论。

Sean Kelly的其他文献

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{{ truncateString('Sean Kelly', 18)}}的其他基金

Collaborative Research [FW-HTF-RL]: Enhancing the Future of Teacher Practice via AI-enabled Formative Feedback for Job-Embedded Learning
协作研究 [FW-HTF-RL]:通过人工智能支持的工作嵌入学习形成性反馈增强教师实践的未来
  • 批准号:
    2326169
  • 财政年份:
    2023
  • 资助金额:
    $ 5.95万
  • 项目类别:
    Standard Grant
SBIR Phase II: Artificially Intelligent Solution to Maximize Value Creation and Upcycling Potential of Aluminum Scrap
SBIR 第二阶段:人工智能解决方案,最大限度地提高废铝的价值创造和升级回收潜力
  • 批准号:
    2026106
  • 财政年份:
    2020
  • 资助金额:
    $ 5.95万
  • 项目类别:
    Cooperative Agreement
CREST-Postdoctoral Research Fellowship: Cross-Ecosystem Interactions and the Transport of Aquatic Contaminants to Terrestrial Food Webs within Mangrove Forests
CREST-博士后研究奖学金:跨生态系统相互作用和水生污染物向红树林内陆地食物网的传输
  • 批准号:
    1914750
  • 财政年份:
    2019
  • 资助金额:
    $ 5.95万
  • 项目类别:
    Standard Grant
SBIR Phase I: Artificially Intelligent Solution to Maximize Value Creation and Upcycling Potential of Aluminum Scrap
SBIR 第一阶段:人工智能解决方案,最大限度地提高废铝的价值创造和升级回收潜力
  • 批准号:
    1843858
  • 财政年份:
    2019
  • 资助金额:
    $ 5.95万
  • 项目类别:
    Standard Grant
EXP: Collaborative Research: Cyber-enabled Teacher Discourse Analytics to Empower Teacher Learning
EXP:协作研究:基于网络的教师话语分析,增强教师学习能力
  • 批准号:
    1735785
  • 财政年份:
    2017
  • 资助金额:
    $ 5.95万
  • 项目类别:
    Standard Grant

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