Collaborative Research: Controlling Surface Damage in Machining of Hierarchical Biological Composites
协作研究:控制多级生物复合材料加工中的表面损伤
基本信息
- 批准号:1031244
- 负责人:
- 金额:$ 22.09万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2010
- 资助国家:美国
- 起止时间:2010-09-01 至 2016-08-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The research objective of this Collaborative Research award is to develop capabilities for machining structural biological composites such as bone and nacre with minimal surface damage. These biological composites exhibit many levels of hierarchical structures from macroscopic to microscopic length scales, and novel structural mechanical properties. The research approach will utilize novel diagnostic instruments for studying deformation/fracture in biological composites and high-resolution optical techniques for analysis of deformation in machining. Modeling structured around finite element analysis and moving heat source theory will be used to predict the thermomechanical state of the composite surfaces created by cutting. Model predictions will be compared with the experimental observations. By integrating these results, recommendations will be developed for improved cutting procedures that will minimize surface damage in this class of structural bio-materials.If successful, the broader impact of the results will be new cutting methodologies for the bio-inspired structural materials of the future, and improved procedures for surgery that minimize damage to bone and tissue. The results will be of value also in understanding deformation and cutting of complex bio-inspired (structural) materials of the future and soft matter, and for continued development of diagnostic instrumentation for biological composites. Complementing the research is an education and training program that includes development of a bone cutting test-bed for practitioners and interns, student internships, seminar series webcast, and a modest focus on fostering entrepreneurship in graduate study.
这项合作研究奖的研究目标是开发加工结构生物复合材料的能力,如骨和珍珠层,表面损伤最小。这些生物复合材料表现出从宏观到微观长度尺度的多层次结构,以及新颖的结构力学性能。该研究方法将利用新型诊断仪器研究生物复合材料的变形/断裂,并利用高分辨率光学技术分析加工中的变形。围绕有限元分析和移动热源理论构建的建模将用于预测由切割产生的复合材料表面的热机械状态。模型预测将与实验观察结果进行比较。通过整合这些结果,将为改进切割程序提出建议,以最大限度地减少此类结构生物材料的表面损伤。如果成功,这些结果的更广泛影响将是未来生物启发结构材料的新切割方法,以及最大限度地减少对骨骼和组织损伤的改进手术程序。研究结果也将有助于理解未来复杂生物启发(结构)材料和软物质的变形和切割,并继续开发生物复合材料的诊断仪器。补充研究是一个教育和培训计划,其中包括开发一个骨切割试验台的从业人员和实习生,学生实习,研讨会系列网络广播,并在研究生学习中培养创业精神适度的重点。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Henry Yang其他文献
Genomewide Expression Profiling in the Zebrafish Embryo Identifies Target Genes Regulated by Hedgehog Signaling During Vertebrate Development
斑马鱼胚胎的全基因组表达谱鉴定了脊椎动物发育过程中 Hedgehog 信号调节的靶基因
- DOI:
10.1534/genetics.106.061523 - 发表时间:
2006 - 期刊:
- 影响因子:3.3
- 作者:
Jun Xu;B. P. Srinivas;Shang Yew Tay;A. Mak;Xianwen Yu;S. Lee;Henry Yang;K. Govindarajan;Bernard Leong;G. Bourque;Sinnakarupan Mathavan;Sudipto Roy - 通讯作者:
Sudipto Roy
ZRSR2 Mutations Cause Dysregulated RNA Splicing in MDS
ZRSR2 突变导致 MDS 中 RNA 剪接失调
- DOI:
- 发表时间:
2014 - 期刊:
- 影响因子:0
- 作者:
Vikas Madan;Deepika Kanojia;Li Jia;Ryoko Okamoto;Aiko Sato-Otsubo;Alexander Kohlmann;Masashi Sanada;Vera Grossmann;Janani Sundaresan;Yuichi Shiraishi;Satoru Miyano;Felicitas Thol; Arnold Ganser;Henry Yang;Torsten Haferlach;Seishi Ogawa;and - 通讯作者:
and
Spectroscopic ellipsometry optical critical dimension measurements of templates and imprinted resist for patterned magnetic media applications
用于图案化磁性介质应用的模板和压印抗蚀剂的光谱椭圆光度光学临界尺寸测量
- DOI:
10.1116/1.3507888 - 发表时间:
2010 - 期刊:
- 影响因子:0
- 作者:
Zhaoning Yu;J. Hwu;Yongdong Liu;Zhenpeng Su;Henry Yang;Hongying Wang;Wei Hu;Yuan Xu;Nobuo Kurataka;Y. Hsu;Shifu Lee;Gene Gauzner;Kim Y. Lee;D. Kuo - 通讯作者:
D. Kuo
A Unifying Mechanism for Cancer Cell Death through Ion Channel Activation by HAMLET
HAMLET 通过离子通道激活实现癌细胞死亡的统一机制
- DOI:
- 发表时间:
2013 - 期刊:
- 影响因子:3.7
- 作者:
P. Storm;Thomas Kjaer Klausen;M. Trulsson;James Ho CS;Marion Dosnon;T. Westergren;Yinxia Chao;Anna Rydström;Henry Yang;S. Pedersen;C. Svanborg - 通讯作者:
C. Svanborg
The polyamine regulator AMD1 up-regulates spermine levels to drive epidermal differentiation.
多胺调节剂 AMD1 上调精胺水平以驱动表皮分化。
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:6.5
- 作者:
A. Rahim;H. Lim;Christina Yan Ru Tan;Li‐wei Jia;V. Leo;T. Uemura;J. Hardman;J. Common;T. Lim;S. Bellanger;R. Paus;K. Igarashi;Henry Yang;L. Vardy - 通讯作者:
L. Vardy
Henry Yang的其他文献
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{{ truncateString('Henry Yang', 18)}}的其他基金
LSAMP BD: UC Santa Barbara California Alliance for Minority Participation
LSAMP BD:加州大学圣塔芭芭拉分校加州少数族裔参与联盟
- 批准号:
2404971 - 财政年份:2024
- 资助金额:
$ 22.09万 - 项目类别:
Standard Grant
Study of Cutting Tools and Processes Used in the Natural World to Develop Highly Efficient Manufacturing Processes
研究自然界中使用的切削工具和工艺,以开发高效的制造工艺
- 批准号:
1635503 - 财政年份:2016
- 资助金额:
$ 22.09万 - 项目类别:
Standard Grant
Planning a Partnership Model for a Giant Segmented Mirror Telescope
规划巨型分段镜面望远镜的合作模式
- 批准号:
1241529 - 财政年份:2013
- 资助金额:
$ 22.09万 - 项目类别:
Cooperative Agreement
Collaborative Research: Nanostructured Alloys With Unprecedented Properties
合作研究:具有前所未有的性能的纳米结构合金
- 批准号:
0626541 - 财政年份:2006
- 资助金额:
$ 22.09万 - 项目类别:
Continuing grant
Hybrid Structural Health Monitoring Via Integrated Sensing of Global Vibration and Local Infrared Imaging
通过整体振动和局部红外成像的综合传感进行混合结构健康监测
- 批准号:
0511046 - 财政年份:2005
- 资助金额:
$ 22.09万 - 项目类别:
Standard Grant
Meso-Scale Plasticity and Deformation Processing
细观尺度塑性和变形加工
- 批准号:
0200509 - 财政年份:2003
- 资助金额:
$ 22.09万 - 项目类别:
Continuing Grant
Generic Sensing Modules Development and Hierarchical Technology for Civil and Mechanical Systems
土木和机械系统的通用传感模块开发和分层技术
- 批准号:
0201320 - 财政年份:2002
- 资助金额:
$ 22.09万 - 项目类别:
Standard Grant
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