Conference: 2011 RNA Editing Gordon Research Seminar and Conference to be held in Galveston, TX; January 8-14, 2011

该奖项支持第八届戈登RNA编辑研究会议，该会议将于2011年1月9日至14日在德克萨斯州加尔维斯顿的加尔维斯酒店举行。该奖项还支持相关的戈登研究研讨会，研究生和博士后研究员将于2011年1月8日至9日在同一地点参加由他们组织的会议。这个两年一次的会议是唯一定期召开的专门讨论RNA和DNA编辑和修饰的会议。这次会议将把一小群科学家聚集在一起，包括知名的科学领袖和年轻的科学家，在一个随意的环境中促进参与者之间的非正式讨论。为了促进编辑和修改社区之间的交流，会议计划以主题会议的形式组织，重点关注共同感兴趣的问题。讲座将在上午和晚上进行，下午保留非正式讨论，休闲活动和海报会议。知识的优点。由于研究RNA和DNA编辑和修饰的不同过程的科学家面临着类似的理论和技术挑战，因此这些研究人员在一次会议上进行互动，讨论他们在该领域核心问题背景下的最新发现，这对他们来说是一个巨大的好处。科学家们将被鼓励以演讲或海报的形式展示他们未发表的成果。在2011年的会议上，预计将出现重要和令人兴奋的突破，包括：发现催化多种类型编辑和修饰的新酶；多组分编辑修改机分子部件的识别精确定义来自各种生物体的编辑或修饰酶的靶rna和dna的识别模式；RNA和DNA编辑修饰酶新靶点的鉴定；深入了解这些酶的作用机制；几种酶的结构分析，以及它们结合底物催化反应的机制；对编辑修饰酶和底物rna的生物合成和亚细胞运输有了新的认识，这对它们的生物学很重要；编辑和修改在生物系统中的不同作用的新见解；以及对编辑和修改过程的起源和演变的新见解。参加本次会议的科学家将受益于听到相关系统的最新信息，这些信息可以在他们自己的系统中激发新的见解和实验方法。此外，科学家也将通过学习解决新问题的前沿方法，包括最新的质谱方法、深度测序方法、遗传方法和生物信息学方法，受益匪浅。更广泛的影响。会议的一个主要目标是通过早期传播未发表的结果、讨论该领域新出现的问题以及解释解决这些问题的新技术来促进发现和促进学习。本次会议是唯一一次对这一快速发展领域进行概述的预定会议。它提供了一个独特的机会来讨论新的假设和模型，交流关于新的实验策略的信息，为未来的项目产生想法，并启动合作。会议力求实现性别平衡，并使发言者的种族和地域多样化。在确认的37名发言人、联合主席和联合副主席中，有11名是女性。几位妇女也将主持会议。此外，两位受邀演讲者和戈登研究研讨会的主席是少数族裔。会议的另一个主要目标是鼓励年轻科学家的参与。为促进青年科学家的发展，将鼓励所有参与者提交海报，组织者将从研究生和博士后中选择至少7人，从初级教师中选择至少2人进行平台演讲。此外，还有四名确认邀请的演讲人是初级教员科学家。研究生研究研讨会为研究生和博士后的教育和培训提供了进一步的机会。这个小型科学会议有三个平台会议和一个海报会议，这些小组的与会者可以在一个理想的科学讨论环境中展示和讨论他们的结果。

This award supports the 8th Gordon Research Conference on RNA Editing, which will be held at the Hotel Galvez in Galveston, TX on January 9-14, 2011. The award also supports the associated Gordon Research Seminar at which graduate students and postdoctoral fellows partake in a meeting organized for and by them from January 8-9, 2011 at the same site. This biannual conference is the only regularly scheduled meeting devoted exclusively to RNA and DNA editing and modification. The conference will bring together a small group of scientists, both established scientific leaders and junior scientists, in a casual setting that fosters informal discussion among participants. To promote cross-fertilization between the editing and modification communities, the conference program is organized in thematic sessions that focus on questions of common interest. Talks will be presented in the mornings and evenings, with afternoons reserved for informal discussions, leisure activities, and poster sessions. Intellectual merits. Since scientists investigating the diverse processes of RNA and DNA editing and modification face similar theoretical and technical challenges, there is a huge benefit for these investigators to interact at a single meeting to discuss their recent findings in the context of the central questions in the field. Scientists will be encouraged to present their unpublished results as talks or posters. Important and exciting breakthroughs are expected to be presented at the 2011 meeting, including: the discovery of new enzymes that catalyze diverse types of editing and modification; the identification of molecular parts of multi-component editing and modifying machines; the precise definition of the mode of recognition of target RNAs and DNAs of editing or modifying enzymes from various organisms; the identification of new targets of RNA and DNA editing and modifying enzymes; insights into the mechanism of action of these enzymes; structural analysis of several enzymes, and of the mechanism by which they bind substrates to catalyze reactions; new understanding of the biosynthesis and subcellular trafficking of editing and modification enzymes and of substrate RNAs that are important for their biology; new insights into the diverse roles of editing and modification in biological systems; and new insights into the origin and evolution of editing and modification processes. Scientists attending this meeting will benefit from hearing the latest information in related systems, which can provoke new insights and experimental approaches in their own system. Furthermore, scientists will also benefit immensely by learning about the cutting edge methods by which new questions are addressed, including the latest mass spectrometry methods, deep sequencing methods, genetic approaches, and bioinformatic methods.Broader impacts. A major goal of the conference is to advance discovery and to promote learning by early dissemination of unpublished results, by discussion of emerging questions in the field, and by explanation of new techniques to address these questions. This conference is the only scheduled meeting that provides an overview of this rapidly growing field. It provides a unique opportunity to discuss new hypotheses and models, to exchange information about new experimental strategies, to generate ideas for future projects, and to initiate collaborations. The meeting strives for gender balance and an ethnically and geographically diverse group of speakers. Eleven of the thirty-seven confirmed speakers, the co-chair, and the co-vice chair are women. Several women will also chair sessions. In addition, two of the invited speakers and the chair of the Gordon Research Seminar are minorities. A further major goal of the conference is to encourage participation of junior scientists. To promote junior scientists, all participants will be encouraged to present posters, from which the organizers will choose at least seven from graduate students and postdoctoral fellows and at least two from junior faculty to present platform talks. In addition, there are four confirmed invited speakers who are junior faculty scientists. The Graduate Research Seminar offers a further opportunity for the education and training of graduate students and postdoctoral fellows. This mini-scientific meeting features three platform sessions and a poster session in which attendees in these groups can present and discuss their results in a setting ideal for scientific discussion.