MRI: Acquisition of Instrumentation for Transmission Electron Microscopy at the University of Hawaii

这一重大研究仪器奖用于资助夏威夷大学马诺阿分校(UHM)购买一台新的透射电子显微镜(TEM)和一台新的超显微切割机，以支持生物学、材料科学和工程方面的研究和培训。电子显微镜和超微切割机取代了研究人员在回答进化、发育、生理学、细胞生物学、生态学、海洋学、气候变化和热带农业等基本问题时使用的老化设备。新的仪器支持NSF和其他资助的广泛生物学专业领域的研究，包括：海洋病毒生态学；海洋和淡水藻类的生物多样性；基础植物细胞生物学；海洋无脊椎动物繁殖、幼虫定居和变态；无脊椎动物髓鞘的进化；神经干细胞生物学；小鼠Y染色体基因在受精中的作用；以及其他。此外，UHM生物电子显微镜设施在许多教育和推广活动中使用了新的显微镜。电子显微镜用于当地公立和私立学校K-12科学班的演示，作为生物和工程本科和研究生大学课程的实验室演示和课程的一部分，用于社区学院教职员工和学生的培训计划，其他专业研讨会，以及本科生和研究生和博士后助理与UHM教师一起进行研究。这些研究和教学工作的结果将通过摘要和同行评议的出版物以及学生和教职员工积极参加专业会议的方式广泛传播。

This Major Research Instrumentation award funds the acquisition of a new transmission electron microscope (TEM) and a new ultramicrotome to support research and training in biology, materials science and engineering at The University of Hawaii at Manoa (UHM). The TEM and ultramicrotome replace aging equipment used by researchers answering fundamental questions in evolution, development, physiology, cell biology, ecology, oceanography, climate change and tropical agriculture. The new instrumentation supports NSF and other funded research in a broad range of biological specializations including: marine viral ecology; biodiversity of marine and freshwater algae; basic plant cell biology; marine invertebrate reproduction, larval settling and metamorphosis; evolution of invertebrate myelin; neural stem cell biology; role of mouse Y chromosome genes in fertilization; and others. Furthermore, the UHM Biological Electron Microscopy Facility uses the new microscope in many educational and outreach activities. The TEM is used for demonstrations for K-12 science classes of local public and private schools, as part of laboratory demonstrations and sessions for undergraduate and graduate university courses in biology and engineering, in a training program for community college faculty and students, other specialty workshops, and for undergraduate and graduate students and postdoctoral associates conducting research with UHM faculty. The results of these research and teaching efforts will be broadly disseminated through abstracts and peer reviewed publications, as well as by active participation of students and faculty at professional meetings