MRI: Acquisition of a Laser Scanning Microscope with Multi-spectral Imaging and Super-resolution

MRI：获取具有多光谱成像和超分辨率的激光扫描显微镜

• 批准号: 1828262
• 负责人: Marilyn Dunlap
• 金额: $ 52.05万
• 依托单位: University of Hawaii
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-10-01 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1828262&HistoricalAwards=false
• 关键词: MRI; Acquisition; Laser; Scanning; Microscope

An award is made to the University of Hawaii at Manoa (UHM) to acquire a new laser scanning microscope (LSM) with multi-spectral imaging and super-resolution capabilities to support research and training in the life sciences. The LSM will be used for demonstrations for K-12 science classes of local public and private schools, as part of laboratory demonstrations and sessions for undergraduate and graduate university courses in the life sciences, participants in NSF REU programs and in other specialty workshops, and by undergraduate and graduate students and postdoctoral associates conducting research with UHM faculty. Attracting youth to careers in the sciences and training the next generation of scientists, engineers and educators in advanced techniques are major goals of our facility and this institution.The requested LSM will be used by researchers to answer fundamental questions in cell biology, developmental biology, ecology, marine biology, microbiology, oceanography, symbiosis and tropical agriculture. The new instrument will support NSF- and other funded research in a broad range of life sciences including: marine invertebrate-bacterial symbiosis; structure and function of marine bacterial communities; plant-fungal symbioses; crustacean peptide hormones; protein expression and enzyme function in a model plant; bacterial biofilms in marine larval settling; amphibian-microbe-fungal associations; and marine copepod population structure. The results from these studies will be published in scientific peer-reviewed journals, presented at scientific meetings, and used in both teaching and public outreach activities.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

授予位于马诺阿的夏威夷大学（UHM）一个新的激光扫描显微镜（LSM），该显微镜具有多光谱成像和超分辨率能力，以支持生命科学的研究和培训。LSM将用于当地公立和私立学校K-12科学课程的演示，作为实验室演示和本科生和研究生大学生命科学课程课程的一部分，NSF REU课程和其他专业研讨会的参与者，以及与UHM教师进行研究的本科生和研究生以及博士后研究员。吸引年轻人从事科学事业，培养下一代科学家，工程师和教育工作者的先进技术是我们的设施和这个机构的主要目标。所要求的LSM将被研究人员用来回答细胞生物学，发育生物学，生态学，海洋生物学，微生物学，海洋学，共生和热带农业的基本问题。新仪器将支持国家科学基金会和其他资助的广泛生命科学研究，包括：海洋无脊椎动物-细菌共生;海洋细菌群落的结构和功能;植物-真菌共生;甲壳类肽激素;模型植物中的蛋白质表达和酶功能;海洋幼虫沉降中的细菌生物膜;两栖动物-微生物-真菌协会;海洋桡足类种群结构。 这些研究的结果将发表在同行评审的科学期刊上，在科学会议上发表，并用于教学和公共宣传活动。该奖项反映了NSF的法定使命，并被认为值得通过使用基金会的知识价值和更广泛的影响审查标准进行评估来支持。

项目成果

Description of Echthrogaleus spinulus n. sp. (Copepoda: Pandaridae) parasitic on a torpedo ray from the central Pacific Ocean utilising a morphological and molecular approach

Echthrogaleus spinulus n. 的描述

• DOI: 10.1007/s11230-019-09885-5
• 发表时间: 2019
• 期刊: Systematic Parasitology
• 影响因子: 1.3
• 作者: Morales-Serna, F. Neptalí;Crow, Gerald L.;Montes, Martin M.;González, M. Teresa
• 通讯作者: González, M. Teresa

Interactions of Symbiotic Partners Drive the Development of a Complex Biogeography in the Squid-Vibrio Symbiosis

• DOI: 10.1128/mbio.00853-20
• 发表时间: 2020-05-01
• 期刊: MBIO
• 影响因子: 6.4
• 作者: Essock-Burns, Tara;Bongrand, Clotilde;McFall-Ngai, Margaret J.
• 通讯作者: McFall-Ngai, Margaret J.

The cytokine MIF controls daily rhythms of symbiont nutrition in an animal–bacterial association

细胞因子 MIF 控制动物与细菌协会中共生营养的日常节律

• DOI: 10.1073/pnas.2016864117
• 发表时间: 2020
• 期刊: Proceedings of the National Academy of Sciences
• 作者: Koch, Eric J.;Bongrand, Clotilde;Bennett, Brittany D.;Lawhorn, Susannah;Moriano-Gutierrez, Silvia;Pende, Marko;Vadiwala, Karim;Dodt, Hans-Ulrich;Raible, Florian;Goldman, William
• 通讯作者: Goldman, William