Further Discovery and Elaboration of Metallacrowns

化学结构，动力学和机制项目支持密歇根大学安娜堡分校的Vincent L. Pecoraro教授，他的研究强调金属冠的发展，金属基分子识别剂最终可能用于实际应用。两个关键目标指导金属冠的研究。首先是了解这些寄主与各种寄主在固态和溶液中的分子识别。佩科拉罗教授希望利用手性金属冠腔内的环境来进行催化化学转化。第二个目标是利用金属冠的固态特性来制造手性、软非线性光学材料、多孔固体和分子磁体。如果成功的话，分子磁体将彻底改变数据存储，并为磁性现象提供更大的基础见解。在美国国家科学基金会化学部化学结构、动力学和机制项目的支持下，佩科拉罗教授探索了金属微粒作为分子识别剂、催化剂、光学材料和分子磁体的用途。这项工作专门针对这些材料作为催化剂的使用，以及为非线性光学材料应用中显示二次谐波产生的客人设计光学透明手性隔间。佩科拉罗教授将继续在培养各级科学家以及在他的实验室和系里指导妇女和少数民族方面保持出色的记录。PI是密歇根化学生物界面培训项目的负责人，该项目指导二年级和三年级的研究生，少数民族参与比例约为17%，女性学员占50%。这个训练计划的目的是交叉训练学生的化学和生物学。

The Chemical Structure, Dynamics and Mechanisms Program supports Professor Vincent L. Pecoraro at the University of Michigan-Ann Arbor whose research emphasizes the development of metallacrowns, metal-based molecular recognition agents that may eventually be used in applications of practical importance. Two key objectives guide the metallacrown research. The first is to understand molecular recognition of these hosts with a variety of guests in the solid state and in solution. Professor Pecoraro hopes to exploit the environment within chiral metallacrown cavities to carry out catalytic chemical transformations. The second objective seeks to exploit the solid state properties of metallacrowns to make chiral, soft non-linear optical materials, porous solids, and molecular magnets. The proposed molecular magnets, if successful, would revolutionize data storage and provide greater fundamental insight on magnetic phenomena.With the support of the Chemical Structure, Dynamics and Mechanisms Program in the Chemistry Division at the National Science Foundation, Professor Pecoraro explores the utility of metallocrowns as molecular recognition agents, catalysts, optical materials and molecular magnets. This work specifically targets the use of these materials as catalysts as well for the design of optically transparent chiral compartments for guests that display second harmonic generation for nonlinear optical materials applications. Professor Pecoraro will continue an excellent track record for producing scientists at all levels and for mentoring women and minorities in both his laboratory and the department. The PI is the Director of the Michigan Chemistry Biology Interface Training Program, which mentors second and third year graduate students and has had about 17% minority participation and 50% female trainees. The intent of this training program is to cross train students in chemistry and biology.