Developing a better understanding of organic reactions under solvent-free ball milling conditions

更好地了解无溶剂球磨条件下的有机反应

• 批准号: 1058627
• 负责人: James Mack II
• 金额: $ 36.78万
• 依托单位: University of Cincinnati Main Campus
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-10-01 至 2015-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1058627&HistoricalAwards=false
• 关键词: Developing; better; understanding; organic; reactions

The Chemical Structure, Dynamics and Mechanisms Program in the Chemistry Division at the National Science Foundation supports Professor James Mack II of the University of Cincinnati, for investigation and development of new solid state organic chemistry reactions using a high speed ball milling process. The goal of this work is to understand the fundamental principles guiding these novel mechanochemical reactions, with a particular emphasis on heat transfer and mass transfer quantification. Solvent-free reactions are attractive to the chemical industry in terms of reducing the waste stream and saving the energy otherwise expended on solvent synthesis, delivery, storage and recovery/disposal.Broader impacts of this research include its direct applicability to "green" chemistry, where one of the major components of a typical organic reaction, the solvent, is removed. Potential benefits to society include the energy savings from elimination of a significant volume of the reactants, less volatile organic components released into the atmosphere, and a smaller waste stream. Professor Mack is known for building a laboratory atmosphere where undergraduates can succeed, and he is very active in recruiting and mentoring scientists from underrepresented groups.

美国国家科学基金会化学部的化学结构、动力学和机理项目支持辛辛那提大学 James Mack II 教授使用高速球磨工艺研究和开发新型固态有机化学反应。 这项工作的目标是了解指导这些新颖的机械化学反应的基本原理，特别强调传热和传质定量。 无溶剂反应对化学工业很有吸引力，因为它可以减少废物流并节省溶剂合成、输送、储存和回收/处置所消耗的能源。这项研究的更广泛影响包括其对“绿色”化学的直接适用性，其中典型有机反应的主要成分之一——溶剂被去除。 对社会的潜在好处包括消除大量反应物而节省能源、释放到大气中的挥发性有机成分更少以及废物流更少。 麦克教授以营造一个让本科生能够取得成功的实验室氛围而闻名，他非常积极地招募和指导来自代表性不足群体的科学家。