DISSERTATION RESEARCH: Predation Behavior of Bacteriovorax and Bacteriophages Against Vibrio spp. - Linking Predatory Traits with Systematics of the Bacterial Predator

论文研究：噬菌体和噬菌体对弧菌的捕食行为。

• 批准号: 1110620
• 负责人: Henry Williams
• 金额: $ 1.4万
• 依托单位: Florida Agricultural and Mechanical University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1110620&HistoricalAwards=false
• 关键词: DISSERTATION; RESEARCH; Predation; Behavior; Bacteriovorax

Bacteriovorax are unique predatory bacteria with potential roles and benefits as antibacterial agents to mitigate certain bacterial diseases in plants and animals, controlling bacterial populations and recycling nutrients in the environment. These bacteria may also be an important unexploited source of new novel therapeutic compounds. To realize the full potential of Bacteriovorax, it is necessary to better understand their genome structure and to bring order to the system of classifying and naming them. The purpose of this study is to use whole-genomic sequences to identify the best-performing genes in order to advance the classification and systematics of Bacteriovorax bacteria. The construction of a more accurate phylogenetic tree of Bacteriovorax will provide a framework to define novel isolates in future studies.This information and resulting classification scheme will be disseminated to the scientific community through publications, sequence databases and a website. Florida A&M is a historically black college and university with few applicants submitting DDIG proposals. The student Co-PI will share her experiences in planning and writing the proposal through presentations to inspire others and thus potentially increasing future numbers of proposals from minority students.

卵形杆菌是一种独特的捕食性细菌，具有潜在的抗菌剂作用和益处，可以减轻动植物中的某些细菌疾病，控制细菌数量，并在环境中循环营养物质。这些细菌也可能是新的治疗化合物的一个重要的未开发的来源。为了充分发挥杆菌的潜力，有必要更好地了解它们的基因组结构，并对它们的分类和命名系统进行有序的调整。本研究的目的是利用全基因组序列来确定功能最好的基因，以推进细菌的分类和系统学研究。构建更准确的杆状病毒系统发育树将提供一个框架，在未来的研究中定义新的分离物。这些信息和由此产生的分类方案将通过出版物、序列数据库和网站向科学界传播。佛罗里达农工大学是一所历史悠久的黑人学院和大学，很少有申请者提交DDIG提案。这位学生将通过演讲来分享她在规划和撰写提案方面的经验，以激励其他人，从而可能增加未来来自少数族裔学生的提案数量。