Triangle Center for Excellence for Materials Research and Innovation: Programmable Assembly of Soft Matter

三角材料研究与创新卓越中心：软物质的可编程组装

• 批准号: 1121107
• 负责人: Stefan Zauscher
• 金额: $ 1368万
• 依托单位: Duke University
• 依托单位国家: 美国
• 项目类别: Cooperative Agreement
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-15 至 2018-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1121107&HistoricalAwards=false
• 关键词: Triangle; Center; Excellence; Materials; Research

The Triangle Center of Excellence for Materials Research and Innovation (CEMRI)* will be a national resource for materials science and engineering research and education in the Raleigh-Durham-Chapel Hill (Triangle) area of North Carolina, a thriving technological and economic hub with a high concentration of materials innovation activity in both academia and industry. The Triangle CEMRI will focus on the study and development of soft matter components to be used in programmable assembly and functional and hybrid materials that result from the assembly of these components. It will synergistically leverage existing and complementary strengths of Duke, NC State, UNC-Chapel Hill and North Carolina Central University, a top-ranked public HBCU. The Triangle CEMRI will have a significant impact in soft matter materials science through generation of (i) new fundamental insights and theoretical understanding, (ii) new design principles, (iii) new applications and uses for colloidal and macromolecular materials and their higher order assemblies, and (iv) an integrated education and outreach program. Understanding, harnessing and exploiting the dynamic processes related to the aggregation of multicomponent particulate and macromolecular assemblies represent significant current frontiers in materials research. Two interdisciplinary research groups (IRGs) comprised of leading researchers in materials theory, simulation, synthesis, processing and applications will surmount these frontiers. A Seed-funding program will also be instituted to allow the extension of the Triangle CEMRI's scope to new areas of soft matter research.IRG1: Multicomponent Colloidal Assembly by Comprehensive Interaction Design. The goal of IRG1 is to develop a fundamental understanding of self-assembly of bulk materials from multi-component suspensions of very small particles (colloids). The team will focus on elucidating the fundamental rules that govern programmed colloidal assembly for materials fabrication by design. Ultimately, this work will have ramifications for the production of hybrid photonic and phononic crystals, anisotropic conducting films, self-healing materials, "smart" gels, metamaterials, and other advanced engineering materials. IRG2: Genetically Encoded Polymer Syntax for Programmable Self-Assembly. The overall goal of IRG2 is to establish the rules for the design of "syntactomers" whose phase behaviors facilitate programming of their self-assembly into supramolecular structures. Syntactomers are macromolecules that consist of a collection of "letters" (monomers that can either be amino acids, nucleotides or synthetic components) are arranged within "words" (repeat units), which are in turn arranged by following a syntax - defined as the arrangement of words - into "phrases" (macromolecules). A new paradigm for macromolecular design will lead to new materials to be used as drug delivery vehicles, actuators, nanofibers, switchable membranes, functional connectors, and scaffolds for mineralization, tissue implants or 3-D cell culture.The Triangle CEMRI will coordinate establishment and access to specialized materials research facilities across the Research Triangle. Its researchers will have access to a global network of research resources, including several national laboratories and laboratories in Europe and Asia. Innovation and technology transfer will be enhanced by the Triangle CEMRI activities aimed at facilitating and catalyzing interactions with both large and small industrial and non-profit commercialization and innovation partners. A comprehensive integration of training, educational and outreach activities will take advantage of the high level of scholarship in materials research and related areas in the Research Triangle area. The overarching goal of the Triangle CEMRI in education, training, and outreach is to infuse materials science, engineering and technology education with a new relevance, excitement and value to audiences ranging from G5-12 students, undergraduate students, graduate students, postdoctoral researchers, to the public sector.* an NSF Materials Research Science and Engineering Center (MRSEC)

三角材料研究与创新卓越中心（CEMRI）* 将成为北卡罗来纳州罗利-达勒姆-查佩尔山（三角）地区材料科学和工程研究与教育的国家资源，该地区是一个蓬勃发展的技术和经济中心，在学术界和工业界都高度集中了材料创新活动。三角CEMRI将专注于软物质组件的研究和开发，用于可编程组件以及这些组件组装产生的功能和混合材料。它将协同利用杜克，北卡罗来纳州，北卡罗来纳大学教堂山和北卡罗来纳州中央大学，一个顶级的公共HBCU的现有和互补的优势。三角CEMRI将通过产生（i）新的基本见解和理论理解，（ii）新的设计原理，（iii）胶体和高分子材料及其高阶组件的新应用和用途，以及（iv）综合教育和推广计划，对软物质材料科学产生重大影响。理解、利用和开发与多组分颗粒和大分子组装体聚集相关的动态过程代表了材料研究的重要前沿。由材料理论、模拟、合成、加工和应用领域的领先研究人员组成的两个跨学科研究小组（IRG）将超越这些前沿。一个种子基金计划也将设立，使三角CEMRI的范围扩大到软物质研究的新领域。IRG 1：多组分胶体组装综合交互设计。IRG 1的目标是从非常小的颗粒（胶体）的多组分悬浮液中开发散装材料自组装的基本理解。该团队将专注于阐明通过设计制造材料的程序化胶体组装的基本规则。最终，这项工作将对混合光子和声子晶体，各向异性导电膜，自我修复材料，“智能”凝胶，超材料和其他先进工程材料的生产产生影响。IRG 2：用于可编程自组装的遗传编码聚合物微球。IRG 2的总体目标是建立设计“句法体”的规则，这些句法体的相行为有助于将其自组装编程为超分子结构。句法异构体是由排列在“单词”（重复单元）内的“字母”（可以是氨基酸、核苷酸或合成组分的单体）的集合组成的大分子，所述“单词”（重复单元）又通过遵循句法（定义为单词的排列）排列成“短语”（大分子）。大分子设计的新范式将导致新材料被用作药物输送载体、致动器、纳米纤维、可转换膜、功能连接器和矿化、组织植入或三维细胞培养的支架。三角CEMRI将协调建立和访问整个研究三角的专业材料研究设施。其研究人员将可以访问全球研究资源网络，包括欧洲和亚洲的几个国家实验室和实验室。创新和技术转让将通过CEMRI三角活动得到加强，这些活动旨在促进和促进与大型和小型工业和非营利商业化和创新伙伴的互动。培训，教育和推广活动的全面整合将利用研究三角区材料研究和相关领域的高水平奖学金。三角CEMRI在教育，培训和推广方面的总体目标是为材料科学，工程和技术教育注入新的相关性，兴奋和价值，从G5-12学生，本科生，研究生，博士后研究人员到公共部门。NSF材料研究科学与工程中心（MRSEC）