Central administration: analytical, clinical and model systems platforms

中央管理：分析、临床和模型系统平台

• 批准号: 202068445
• 负责人: Professor Dr. Stefan R. Bornstein, Ph.D.
• 金额: --
• 依托单位: Medizinische Klinik und Poliklinik III
• 依托单位国家: 德国
• 项目类别: Clinical Research Units
• 财政年份: 2011
• 资助国家: 德国
• 起止时间: 2010-12-31 至 2018-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/202068445?language=en
• 关键词: Central; administration; analytical; clinical; model

The proposed Clinical Research Unit (CRU), which will provide a comprehensive focus on the adrenal microenvironment in health and disease, depends crucially on scientific interactions and networking. The success of our integrative and multidisciplinary approach requires an efficient management of clinical studies and resources, including collections and sharing of uniquely linked patient data and human materials, together with availability to all CRU members of state-of-the-art analytical platforms and mouse models. The central administration of clinical protocols, patient data collection, biobanking and complex genetically modified mouse models will accelerate research efforts and enhance collaborative synergisms. Of crucial importance, the central administration will strengthen the mentorship of young physician-scientists and promote equal opportunities by supporting the careers of female scientists and encouraging a family-friendly working atmosphere. This will be accomplished by establishing a network of administrative and support staff, Gerok physician-scientist positions, child care services and training opportunities enhanced by organized seminar and lecture series and exchanges of personnel between the CRU and collaborating outside institutions.

拟议中的临床研究单位（CRU）将全面关注健康和疾病中的肾上腺微环境，关键取决于科学互动和网络。我们的综合和多学科方法的成功需要有效管理临床研究和资源，包括收集和共享独特关联的患者数据和人体材料，以及为所有CRU成员提供最先进的分析平台和小鼠模型。对临床方案、患者数据收集、生物库和复杂的转基因小鼠模型的集中管理将加快研究工作并加强协同增效作用。至关重要的是，中央行政部门将加强对青年医生-科学家的指导，并通过支持女科学家的职业生涯和鼓励关爱家庭的工作氛围来促进机会平等。这将通过建立一个由行政和支助人员、Gerok医生-科学家职位、儿童保育服务和培训机会组成的网络来实现，通过组织研讨会和系列讲座以及CRU与外部合作机构之间的人员交流来加强培训机会。

项目成果

Dipping in Ambulatory Blood Pressure Monitoring Correlates With Overnight Urinary Excretion of Catecholamines and Sodium

• DOI: 10.1111/jch.12791
• 发表时间: 2016-09-01
• 期刊: JOURNAL OF CLINICAL HYPERTENSION
• 影响因子: 2.8
• 作者: Daerr, Roland;Bursztyn, Michael;Eisenhofer, Graeme
• 通讯作者: Eisenhofer, Graeme

Seasonal variation in plasma free normetanephrine concentrations: implications for biochemical diagnosis of pheochromocytoma.

血浆游离去甲肾上腺素浓度的季节性变化：对嗜铬细胞瘤生化诊断的影响

• DOI: 10.1530/eje-13-0673
• 发表时间: 2014
• 期刊: European journal of endocrinology
• 影响因子: 5.8
• 作者: Pamporaki C;Bursztyn M;Reimann M;Ziemssen T;Bornstein SR;Sweep FC;Timmers H;Lenders JW;Eisenhofer G
• 通讯作者: Eisenhofer G