SBIR Phase I: Optically Actuated MRI-Compatible Active Needle for Medical Interventions

SBIR 第一阶段：用于医疗干预的光驱动 MRI 兼容主动针

• 批准号: 1143478
• 负责人: Richard Black
• 金额: $ 15万
• 依托单位: INTELLIGENT FIBER OPTICS SYSTEMS CORP.
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1143478&HistoricalAwards=false
• 关键词: SBIR; Phase; Optically; Actuated; MRI

This Small Business Innovation Research (SBIR) Phase I project aims to develop miniature optically actuated and instrumented tools that can be used during Magnetic Resonance Imaging (MRI) interventions to make them faster and more precise. The initial focus is an active steerable biopsy needle prototype that uses laser heating conducted via optical fibers to a low temperature (50C) shape memory alloy (SMA) actuator located inside the needle. The prototype employs optical fiber sensing of the needle shape and temperature, for control. In contrast to previous "point and shoot" approaches for needle insertion, a physician will be able to stand outside the scanner bore, guiding an MRI compatible needle through the perineum and steering it to the target in the prostate with visual feedback.The broader/commercial impacts of this research include minimally invasive MRI compatible needles, catheters, and apparatus for ablations and brachytherapy. Following development of the active needle, the IFOS team plans integration with MRI scanning software to significantly reduce time and cost, and increase the precision of MRI guided interventions such as biopsy and brachytherapy. Combined optical actuation, temperature profile and shape monitoring can add still more versatility, allowing IFOS to address the sizeable image guided surgery market. IFOS intends to leverage existing products and strategic partnerships to reduce the technical risk and offer its technology in interdisciplinary fields across the image guided medical industry. This research involves the work of a diverse group of researchers, industrial product developers, surgeons and business people with commercial acumen.

该小型企业创新研究(SBIR)第一阶段项目旨在开发可在磁共振成像(MRI)干预过程中使用的微型光学驱动和仪表化工具，以使其更快、更精确。最初的焦点是一种主动可定向活检针原型，它使用通过光纤传导的激光加热到位于针内的低温(50摄氏度)形状记忆合金(SMA)致动器。该样机采用光纤传感针形和温度进行控制。与以前的点射方法不同，医生将能够站在扫描仪孔外，引导与MRI兼容的针穿过会阴，并通过视觉反馈将其引导到前列腺中的靶点。这项研究的更广泛/更广泛的商业影响包括与MRI兼容的微创针、导管以及用于消融和近距离治疗的设备。随着主动针的开发，IFOS团队计划与MRI扫描软件集成，以显著减少时间和成本，并提高MRI引导的干预措施的精度，如活检和近距离放射治疗。结合光学驱动、温度分布和形状监控可以增加更多的通用性，使IFOS能够满足庞大的图像引导手术市场。IFOS打算利用现有产品和战略合作伙伴关系来降低技术风险，并在整个影像引导医疗行业的跨学科领域提供其技术。这项研究涉及不同的研究人员、工业产品开发人员、外科医生和具有商业头脑的商人的工作。