MOLECULAR STRUCTURE AND CHEMICAL REACTIVITY

分子结构和化学反应性

• 批准号: 1148992
• 负责人: Charles Perrin
• 金额: $ 54万
• 依托单位: University of California-San Diego
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-15 至 2017-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1148992&HistoricalAwards=false
• 关键词: MOLECULAR; STRUCTURE; CHEMICAL; REACTIVITY

The Chemical Structure, Dynamics and Mechanisms Program in the Chemistry Division at the National Science Foundation supports Professor Charles L. Perrin of the University of California, San Diego, who will perform research to elucidate the relation between molecular structure and chemical reactivity. The research covers a wide range of topics, including symmetry of hydrogen bonds; isotope effects, conformational effects, the reactivity of a p-benzyne diradical toward nucleophiles, and the reactivity of malonic anhydrides. The success of these studies will rely on powerful and informative nuclear magnetic resonance methods.This is all curiosity-driven basic research. The projects are excellent for training students to formulate and test hypotheses, to ask and answer questions, to solve problems, to use modern instrumentation, to analyze data, and to exercise critical thinking. The eventual utility of these studies remains long-range, inasmuch as they are not aimed at practical application but at developing a thorough understanding that will guide further research. Professor Perrin has been appointed as Chair of an international task force charged with revising the online IUPAC Glossary of Terms Used in Physical Organic Chemistry, which provides a major service to students and researchers.

美国国家科学基金会化学部的化学结构、动力学和机制项目支持查尔斯·L·他将进行研究以阐明分子结构和化学反应性之间的关系。 该研究涵盖了广泛的主题，包括氢键的对称性;同位素效应，构象效应，对苯炔双自由基对亲核试剂的反应性，以及丙二酸酐的反应性。这些研究的成功将依赖于强大而信息丰富的核磁共振方法。这都是好奇心驱动的基础研究。这些项目非常适合培养学生制定和测试假设，提问和回答问题，解决问题，使用现代仪器，分析数据和锻炼批判性思维。这些研究的最终用途仍然是长期的，因为它们的目的不是实际应用，而是为了形成一种指导进一步研究的透彻理解。Perrin教授被任命为负责修订在线IUPAC物理有机化学术语表的国际工作组主席，该术语表为学生和研究人员提供了重要服务。