Switch Angle Sample Spinning Probes and High Resolution Dipolar Recoupling with Quadrupolar Nuclei

切换角度样品旋转探针和四极核高分辨率偶极重耦合

• 批准号: 1152009
• 负责人: Terry Gullion
• 金额: $ 45万
• 依托单位: West Virginia University Research Corporation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-15 至 2016-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1152009&HistoricalAwards=false
• 关键词: Switch; Angle; Sample; Spinning; Probes

In this award, funded by the Chemical Measurement and Imaging Program of the Division of Chemistry, Professor Terry Gullion of West Virginia University and his undergraduate and graduate student researchers will be supported to develop new solid-state nuclear magnetic resonance (NMR) methods for measuring dipolar coupling between nuclei with spin = 1/2 and quadrupolar nuclei. Careful measurement of the coupling between nuclei can yield accurate information on the distance between atoms in chemical materials. Professor Gullion will do this through development of novel sample spinning methods in conjunction with the design and construction of new kinds of probes.Nuclear magnetic resonance spectroscopy is an important physicochemical method that gives precise chemical and structural information. The methods that Prof. Gullion and his student researchers will develop will enable scientists to measure inter-nuclear distances between nuclei that are difficult to deal with, experimentally. The work has the potential to open up new vistas in biological and materials science where the kind of information that can be obtained from these types of experiments is critical in order to relate structure with function. The undergraduate and graduate students working on this project will gain useful experience in building hardware for NMR experiments. As part of this work, Prof. Gullion will also conduct workshops on NMR hardware (transmission line probe) construction for members of the scientific community.

该奖项由化学系化学测量和成像项目资助，西弗吉尼亚大学的Terry Gullion教授及其本科生和研究生研究人员将获得支持，以开发新的固态核磁共振（NMR）方法，用于测量自旋= 1/2的核与四极核之间的偶极耦合。 仔细测量原子核之间的耦合可以得到化学材料中原子之间距离的准确信息。 古利安教授将通过开发新型样品旋转方法以及新型探针的设计和构建来实现这一目标。核磁共振光谱法是一种重要的物理化学方法，可以提供精确的化学和结构信息。 Gullion教授和他的学生研究人员将开发的方法将使科学家能够测量实验上难以处理的原子核之间的核间距离。 这项工作有可能在生物和材料科学领域开辟新的前景，从这些类型的实验中获得的信息对于将结构与功能联系起来至关重要。 参与该项目的本科生和研究生将获得构建核磁共振实验硬件的有用经验。 作为这项工作的一部分，Gullion教授还将为科学界成员举办关于NMR硬件（传输线探头）建设的讲习班。