Integration of scheduling and control using closed loop implementation
使用闭环实现集成调度和控制
基本信息
- 批准号:1159244
- 负责人:
- 金额:$ 22.82万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Continuing Grant
- 财政年份:2012
- 资助国家:美国
- 起止时间:2012-04-15 至 2018-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
1159244IerapetritouSummary: Given the strenuous economic environment and the fierce competition that almost all industrial sectors have to face, a lot of research and development have recently focused on advanced manufacturing. The initiative that the president announced this summer to invest $500M on the Advanced Manufacturing Partnership (AMP) points in this direction. More specifically this effort targets the collaboration of industry, universities, and the federal government "to invest in emerging technologies such as information technology, biotechnology, and nanotechnology". There are already some steps towards this direction that aim in reducing the time to the market and increasing the efficiency of manufacturing processes. This proposal's objective is to develop approaches that can lead to more efficient product operations by incorporating the process dynamics into the production scheduling problem. The full coupling of process control and production scheduling can substantially increase production feasibility and optimality. However, simultaneous consideration of process control and scheduling problems is currently plagued by (a) the lack of communication between the associated research communities; (b) its computational intensity, and (c) the inherently complex nature of manufacturing processes.Intellectual Merit: We propose an integrated approach to address the problem of scheduling considering a closed loop implementation of control in a process level. This will result in more efficient utilization of resources most importantly in the face of disturbances. However the incorporation of control within the already complex scheduling problem results in a very difficult problem and conventional solution methods turn out to be inefficient. The main outcome we are targeting is to provide the decision maker solutions that are optimal in terms of production capacity and feasible in terms of process dynamics in the face of disturbance.To achieve this target, the following ideas will be investigated:1. Integration of closed loop control with short term scheduling following the basic idea of Model Predictive Control (MPC) strategy.2. Investigation of MPC integration using multi-parametric programming.3. Investigation of efficient solution methodologies for the integrated scheduling andcontrol problem.Broader Impact: The ultimate goal of this work is to optimize the production scheduling considering the details of process dynamics. Realistic case studies from chemical and pharmaceutical manufacturing will be utilized to test and verify the results of the proposed analysis tools. The impact of the proposed work goes beyond specific industrial sector since the general ideas and findings can be applied or extended to different types of production facilities. The educational component of the proposed work involves one graduate and two undergraduate students. Funding for the undergraduate students would be pursued through REU initiative. Students affiliated with program SUPER (Science for Undergraduates a Program for Excellence in Research) of Douglass College of Women will be actively involved with this project.
1159244 Ierapetritou摘要:鉴于几乎所有工业部门都必须面对的严峻经济环境和激烈竞争,最近许多研究和开发都集中在先进制造业上。总统今年夏天宣布的向先进制造业伙伴关系(AMP)投资5亿美元的倡议指向了这个方向。更具体地说,这项努力的目标是工业界、大学和联邦政府的合作,“投资于新兴技术,如信息技术、生物技术和纳米技术”。已经有一些朝着这个方向的步骤,旨在减少上市时间和提高制造过程的效率。本提案的目标是开发方法,可以导致更有效的产品操作,将过程动态到生产调度问题。过程控制和生产调度的充分耦合可以大大提高生产的可行性和最优性。然而,同时考虑过程控制和调度问题是目前困扰(a)缺乏相关的研究社区之间的沟通;(B)其计算强度,和(c)固有的复杂性质的制造processs.Intellectual Merit:我们提出了一个综合的方法来解决调度考虑在一个过程中的闭环控制实现的问题。这将导致更有效地利用资源,最重要的是在面临干扰时。然而,在已经很复杂的调度问题中加入控制会导致一个非常困难的问题,并且传统的解决方法被证明是低效的。我们的主要目标是提供决策者的解决方案,是最佳的生产能力和可行的过程动态方面的干扰。为了实现这一目标,以下想法将被调查:1。遵循模型预测控制(MPC)策略的基本思想,将闭环控制与短期调度相结合.多参数规划在MPC积分中的应用研究.研究集成调度和控制问题的高效求解方法。更广泛的影响:这项工作的最终目标是考虑过程动态的细节来优化生产调度。来自化学和制药制造的实际案例研究将被用来测试和验证所提出的分析工具的结果。拟议工作的影响超出了具体的工业部门,因为一般的想法和结论可以应用或扩展到不同类型的生产设施。拟议工作的教育部分涉及一名研究生和两名本科生。将通过REU倡议为本科生提供资金。道格拉斯女子学院SUPER(本科生科学研究卓越计划)项目的学生将积极参与该项目。
项目成果
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Marianthi Ierapetritou其他文献
Application of flowsheet modeling for scheduling and debottlenecking analysis to support the development and scale-up of a plasma-derived therapeutic protein purification process
- DOI:
10.1016/j.bej.2024.109501 - 发表时间:
2024-12-01 - 期刊:
- 影响因子:
- 作者:
Chaoying Ding;Matthew Kujawa;Michael Bartkovsky;Maen Qadan;Marianthi Ierapetritou - 通讯作者:
Marianthi Ierapetritou
Machine learning-based optimization of a multi-step ion exchange chromatography for ternary protein separation
- DOI:
10.1016/j.compchemeng.2024.108642 - 发表时间:
2024-05-01 - 期刊:
- 影响因子:
- 作者:
Chaoying Ding;Marianthi Ierapetritou - 通讯作者:
Marianthi Ierapetritou
Topology-informed derivative-free metaheuristic optimization method
- DOI:
10.1016/j.compchemeng.2024.108973 - 发表时间:
2025-03-01 - 期刊:
- 影响因子:
- 作者:
Ching-Mei Wen;Marianthi Ierapetritou - 通讯作者:
Marianthi Ierapetritou
Effect of material properties on the residence time distribution (RTD) of a tablet press feed frame
- DOI:
10.1016/j.ijpharm.2020.119961 - 发表时间:
2020-12-15 - 期刊:
- 影响因子:
- 作者:
Ryoichi Furukawa;Ravendra Singh;Marianthi Ierapetritou - 通讯作者:
Marianthi Ierapetritou
Using residence time distribution in pharmaceutical solid dose manufacturing – A critical review
- DOI:
10.1016/j.ijpharm.2021.121248 - 发表时间:
2021-12-15 - 期刊:
- 影响因子:
- 作者:
Pooja Bhalode;Huayu Tian;Shashwat Gupta;Sonia M. Razavi;Andres Roman-Ospino;Shahrzad Talebian;Ravendra Singh;James V. Scicolone;Fernando J. Muzzio;Marianthi Ierapetritou - 通讯作者:
Marianthi Ierapetritou
Marianthi Ierapetritou的其他文献
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{{ truncateString('Marianthi Ierapetritou', 18)}}的其他基金
FMRG: Eco: A Systems-Enabled Paradigm Shift for Modular Sustainable Chemical Manufacturing
FMRG:Eco:系统支持的模块化可持续化学制造范式转变
- 批准号:
2134471 - 财政年份:2022
- 资助金额:
$ 22.82万 - 项目类别:
Standard Grant
Supply Chain Decision Making Framework Considering Uncertainty
考虑不确定性的供应链决策框架
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2217472 - 财政年份:2022
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$ 22.82万 - 项目类别:
Standard Grant
SusChem Collaborative Research: Process Optimization of Novel Routes for the Production of bio-based Para-Xylene
SusChem 合作研究:生物基对二甲苯生产新路线的工艺优化
- 批准号:
2005905 - 财政年份:2019
- 资助金额:
$ 22.82万 - 项目类别:
Continuing Grant
EAGER: Cybermanufacturing: Advanced Modeling and Information Management in Pharmaceutical Manufacturing
EAGER:网络制造:药品制造中的高级建模和信息管理
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1547171 - 财政年份:2015
- 资助金额:
$ 22.82万 - 项目类别:
Standard Grant
SusChem Collaborative Research: Process Optimization of Novel Routes for the Production of bio-based Para-Xylene
SusChem 合作研究:生物基对二甲苯生产新路线的工艺优化
- 批准号:
1434548 - 财政年份:2014
- 资助金额:
$ 22.82万 - 项目类别:
Continuing Grant
Workshop on Process Intensification September 30-October 1, 2014, Arlington, VA
过程强化研讨会 2014 年 9 月 30 日至 10 月 1 日,弗吉尼亚州阿灵顿
- 批准号:
1450788 - 财政年份:2014
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Standard Grant
Innovative methodologies for integrated planning and scheduling and industrial applications
集成规划和调度以及工业应用的创新方法
- 批准号:
0966861 - 财政年份:2010
- 资助金额:
$ 22.82万 - 项目类别:
Standard Grant
Commercializing of Continuous Pharmaceutical Manufacturing Technology
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- 批准号:
0951845 - 财政年份:2009
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$ 22.82万 - 项目类别:
Standard Grant
Systematic Mathematical Strategies for Stochastic Modeling and Uncertainty in Production Planning and Scheduling
生产计划和调度中随机建模和不确定性的系统数学策略
- 批准号:
0625515 - 财政年份:2006
- 资助金额:
$ 22.82万 - 项目类别:
Standard Grant
Travel Grant: FOCAPO 2008: Multi-Scale Integration of R&D, Manufacturing, and Optimization for Enterprise-Wide Operations
旅行补助金:FOCAPO 2008:R 的多尺度整合
- 批准号:
0638947 - 财政年份:2006
- 资助金额:
$ 22.82万 - 项目类别:
Standard Grant
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