MRI: Acquisition of a MALDI-ToF Mass Spectrometer

MRI：购买 MALDI-ToF 质谱仪

• 批准号: 1229292
• 负责人: Hans Schanz
• 金额: $ 21.9万
• 依托单位: Georgia Southern University Research and Service Foundation, Inc
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2015-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1229292&HistoricalAwards=false
• 关键词: MRI; Acquisition; MALDI; ToF; Mass

This award for a benchtop MALDI-ToF mass spectrometer to Georgia Southern University will impact a number of researchers in the Chemistry and Physics Departments there as well as researchers at Armstrong Atlantic State University. The instrument will enhance the following research projects: 1) artificial bioactive polymers; new artificial polymers via hydroamination; 2) ROMP copolymers for binding to hemoglobin-based oxygen carrier; 3) biomass for catalytic conversion into liquid fuels; 4) repellent polymeric coatings and pH-responsive polymers; 5) potential iron chelation therapy drugs; 6) modified hemoglobin products; 7) porphyrin-based singlet oxygen sensitizers; and, 8) investigation of proteins in nanoparticles. The MALDI-ToF mass spectrometer will enhance the research culture at Georgia Southern by supporting the team's efforts in the multi-disciplinary and collaborative Material Science research focus area on campus. Additionally, the instrument will improve undergraduate research training by enabling 'hands-on' experiences. The instrument will also enrich the curriculum through the integration of a practical instrument component into lecture classes and laboratory courses for undergraduate students. Finally, a multiple-student project is planned incorporating the instrument in the development of a YouTube video, which introduces and illustrates mass-spectroscopy techniques, in particular MALDI-ToF.

这份授予佐治亚南方大学的台式MALDI-ToF质谱仪的合同将影响该校化学系和物理系以及阿姆斯特朗大西洋州立大学的许多研究人员。该仪器将加强以下研究项目：1)人工生物活性聚合物；氢胺化合成的新型人工聚合物2)结合血红蛋白基氧载体的ROMP共聚物；3)催化转化为液体燃料的生物质；4)拒水性聚合物涂层和ph响应性聚合物；5)潜在的铁螯合治疗药物；6)改性血红蛋白制品；7)卟啉基单线态氧敏化剂；8)纳米颗粒中蛋白质的研究。MALDI-ToF质谱仪将通过支持该团队在校园多学科和合作材料科学研究重点领域的努力，加强佐治亚南方大学的研究文化。此外，该仪器将通过提供“实践”经验来改善本科生的研究培训。该仪器还将通过将实用仪器组件整合到本科学生的课堂和实验课程中来丰富课程。最后，一个由多名学生组成的项目计划将该仪器纳入YouTube视频的开发中，该视频介绍并说明了质谱技术，特别是MALDI-ToF。