Optofluidic Tweezers
Optofluidic Tweezers
批准号:
1232226
负责人:
Amar Basu
金额:
$33.53万
依托单位:
依托单位国家:
美国
项目类别:
Standard Grant
财政年份:
2012
资助国家:
美国
项目状态:
已结题
起止时间:
2012-08-01 至 2018-07-31
关键词:
中文摘要
本研究的目的是研究一种新型的光学镊子,它可以用大的力捕获和操纵液滴。这种方法被称为光流体镊子(OFT),是基于光的光刻转换成三维受限的热毛细微涡,该微涡使液滴在聚焦激光的轴上对齐。知识价值。OFT依赖于毛细管力,这是一种与传统光学镊子根本不同的机制。它可以获得µN范围的力,比光镊大10万倍,比光电镊大1000倍。这种独特的功能使OFT成为一种潜在的变革性方法,可以在广泛的长度范围内进行液体操作。本研究将通过对流场、温度分布、保持力、几何缩放和材料特性的系统研究,建立对能量转导和捕获机制的基本理解。它还将为基于oft的操作创建一个原型系统。更广泛的影响。光学操纵工具广泛应用于生物学、物理学和工程学,特别是在微纳米尺度上。由于其强大的力量,OFT可以将这些功能扩展到毫米尺度,从而在电子制造和芯片实验室系统中实现新的应用。这个高度跨学科的项目结合了光学、流体动力学和界面现象,为培养研究生和本科生提供了一个独特的平台。私家侦探会利用韦恩州立大学吗?美国建立了招募未被充分代表的少数族裔的渠道。PI还将开发一个?果冻微流体?这是一个由美国国家科学基金会赞助的面向K-12学生的纳米级科学教育项目。
英文摘要
The objective of this research is to investigate a novel class of optical tweezers which can trap and manipulate liquid droplets with large force. The approach, termed optofluidic tweezers (OFT), is based on the photomechanical conversion of light into 3-dimensionally confined thermocapillary microvortices which align a droplet on the axis of a focused laser.Intellectual Merit. OFT relies on capillary forces, a mechanism fundamentally different from traditional optical tweezers. It can attain forces in the µN range, which is 100,000X larger than optical tweezers and 1,000X larger than optoelectronic tweezers. This unique feature makes OFT a potentially transformative approach for liquid manipulation over a wide range of length scales. This research will build a fundamental understanding of the energy transduction and trapping mechanism through the systematic study of flow fields, temperature profiles, holding forces, geometric scaling, and material properties. It will also create a prototype system for OFT-based manipulation.Broader Impacts. Optical manipulation tools are broadly used in biology, physics, and engineering, typically at the micro and nanoscale. Due to its large force, OFT can extend these capabilities to the millimeter scale, enabling new applications in electronics manufacturing and lab-on-a-chip systems. This highly interdisciplinary project combines optics, fluid dynamics, and interfacial phenomena, providing a unique platform for training graduate and undergraduate students. The PI will leverage Wayne State University?s established channels for recruiting underrepresented minorities. The PI will also develop a ?jello microfluidics? module for Detroit Science Center Nanodays, an NSF-sponsored program for nanoscale science education targeted to K-12 students.
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专著(0)
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会议论文
MRI: Acquisition of a Nanoscale 3D printer for Fundamental and Applied Research at Wayne State University and Southeast Michigan
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批准号:2116715
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项目类别:Standard Grant
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资助金额:$62.83万
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财政年份:2021
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负责人:Amar Basu
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依托单位:
UNS: Fractionation, purification, and analysis of gases in microbubbles
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批准号:1512544
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项目类别:Standard Grant
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资助金额:$30.03万
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财政年份:2015
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负责人:Amar Basu
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依托单位:
Tensiophoresis: Label Free Droplet Sorting in Surfactant Microgradients
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批准号:1236764
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项目类别:Standard Grant
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资助金额:$30.08万
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财政年份:2012
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负责人:Amar Basu
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依托单位:
BRIGE: Microfractionation in Droplets (µFD) - Linking Proteomic Separations to High Throughput Functional Screening
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批准号:1032603
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项目类别:Standard Grant
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资助金额:$17.5万
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财政年份:2010
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负责人:Amar Basu
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依托单位:
国内基金
海外基金
基于“3D-Tweezers”冷冻金探针和深度学习识别的农产品中真菌毒素快速检测技术研究
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批准号:--
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项目类别:面上项目
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资助金额:55万元
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批准年份:2021
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负责人:高志贤
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依托单位: