Collaborative Research: GENETICS OF LIFE CYCLE EVOLUTION AND THE EFFECTS ON TEMPORAL ISOLATION AND GENE FLOW

合作研究：生命周期进化的遗传学及其对时间隔离和基因流的影响

• 批准号: 1256688
• 负责人: Jeremy Searle
• 金额: $ 34.76万
• 依托单位: Cornell University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1256688&HistoricalAwards=false
• 关键词: Collaborative; Research; GENETICS; LIFE; CYCLE

The long-term goal of the research is to understand the process of speciation, in which one species splits into two, often through the evolution of multiple forms of reproductive isolation. The project focuses on reproductive isolation that occurs because of differences in the timing of major life cycle events, a widespread and potentially major impetus for speciation when differences in time of reproduction restrict gene flow. In a multi-pronged approach that applies high-throughput DNA sequencing, genetic mapping, population genomic analysis, metabolic profiling and field experiments the research will examine the genetic basis of life cycle variation and temporal reproductive isolation in the European corn borer moth (Ostrinia nubilalis), and evaluate the consequence of these differences in preventing gene flow between populations in nature. These experiments will provide a rare glimpse into the role of temporal isolation in origin of new species. Although a superb model for speciation, the European corn borer is also a major pest of corn and other crops, costing the United States ~$1B each year. By leveraging the moth as an organism of both scientific and economic interest, the research builds community partnerships to simultaneously promote basic scientific discovery, public understanding of the relevance of evolution in daily life, and sustainable agriculture.

这项研究的长期目标是了解物种形成的过程，在这个过程中，一个物种通常通过多种形式的生殖隔离进化而分裂成两个物种。该项目的重点是由于主要生命周期事件发生时间的差异而导致的生殖隔离，当繁殖时间的差异限制了基因流动时，这是物种形成的广泛和潜在的主要推动力。该研究将采用多管齐下的方法，包括高通量DNA测序、遗传图谱、种群基因组分析、代谢谱和实地实验，研究欧洲玉米螟蛾（Ostrinia nubilalis）生命周期变异和时间生殖隔离的遗传基础，并评估这些差异在防止自然种群之间基因流动方面的后果。这些实验将提供一个难得的机会来了解时间隔离在新物种起源中的作用。虽然是物种形成的绝佳典范，但欧洲玉米螟也是玉米和其他作物的主要害虫，每年给美国造成约10亿美元的损失。通过利用飞蛾作为一种具有科学和经济利益的生物，该研究建立了社区伙伴关系，同时促进基础科学发现，公众对日常生活中进化相关性的理解，以及可持续农业。