REU Site: Multifunctional Nanomaterials

REU 网站：多功能纳米材料

• 批准号: 1262075
• 负责人: Michelle Richards-Babb
• 金额: $ 32万
• 依托单位: West Virginia University Research Corporation
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-04-15 至 2016-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1262075&HistoricalAwards=false
• 关键词: REU; Site; Multifunctional; Nanomaterials

TECHNICAL SUMMARY: With funding provided by the National Science Foundation's Divisions of Materials Research and Chemistry, West Virginia University will host a Multifunctional Nanomaterials Research Experiences for Undergraduates (REU) Site. This project focuses on solving fundamental engineering and scientific problems related to surfaces, toxicity and fluid transport in a variety of configurations both experimentally and theoretically. Projects will focus on multifunctional nanomaterials and fabrication of complex devices with applications to biometrics, environmental monitoring, early disease detection, and energy efficiency. The approach includes: use of scanning probe acceleration microscopy to study nanoscale mechanical responses of biologically relevant surfaces; synthesis of fullerene fragments as templates for carbon nanotubes; use of ultrafast laser spectroscopy to characterize and coherently control nanophotonic materials for optical detection and light harvesting devices; use of microsurgery to assess microvascular toxicity after exposure to engineered nanomaterials; cell-based monitoring assays and characterization of cell fate to assess toxicity of nanomaterials; modeling of liver functions using P450 enzymes attached to self-assembled monolayers with subsequent elucidation of the role of substrate binding in controlling electron transfer and enzyme activity of P450; and fabrication and characterization of a) multiferroic thin films for integration into memory devices, b) non-mechanical valves composed of nanogels for point-of-care testing, and c) microfluidic polydimethylsiloxane tissue bioreactors for characterization of carbon nanotubes and their chronic effects on lung epithelial cells. REU participants carry out their research in collaboration with faculty and graduate students and are trained on modern scientific equipment (AFM, X-ray reflectivity and diffraction, capillary electrophoresis, photolithography, SEM, etc.) and/or in the use of computer modeling software. The project includes training that is important to the development of future scientific leaders, e.g. scientific ethics, laboratory safety, communication, collaboration and technical presentation skills.NON-TECHNICAL SUMMARY: Undergraduate student participants (10 per year) in this Research Experiences for Undergraduates (REU) site are integrated into scientific investigations in order to train the next generation of U.S. scientists and engineers. This project primarily supports participation of women, underrepresented minorities, U.S. Armed Forces veterans and persons from economically depressed areas (e.g., Appalachia). Involvement will improve the likelihood that participants will enroll in graduate-level science and engineering education programs, thereby improving the scientific workforce of the U.S. Participants are provided with a comprehensive program that rapidly moves them toward research independence. This preparation includes day-to-day research work on nanomaterials-related projects intermingled with training in: the research process and cutting-edge scientific instrumentation; laboratory safety and scientific ethics; and communication and collaboration. Research projects are geared to the eventual development of new hybrid electronic and photonic devices that will lead to a new generation of biometric, environmental monitoring, early disease detection, and energy efficient device applications.

技术概要：在国家科学基金会材料研究和化学部门的资助下，西弗吉尼亚大学将举办一个多功能纳米材料研究经验的本科生（REU）网站。 该项目的重点是解决实验和理论上的各种配置中与表面，毒性和流体传输相关的基本工程和科学问题。 项目将侧重于多功能纳米材料和复杂设备的制造，应用于生物识别，环境监测，早期疾病检测和能源效率。 该方法包括：使用扫描探针加速显微镜研究生物相关表面的纳米级机械响应;合成富勒烯片段作为碳纳米管的模板;使用超快激光光谱学表征和相干控制用于光学检测和光收集装置的纳米光子材料;使用显微外科手术评估暴露于工程纳米材料后的微血管毒性;基于细胞的监测分析和细胞命运表征，以评估纳米材料的毒性;使用附着于自组装单层的P450酶对肝功能建模，随后阐明底物结合在控制电子转移和P450酶活性中的作用;以及制造和表征a）用于集成到存储器装置中的多铁性薄膜，B）用于即时检测的由纳米凝胶组成的非机械阀，和c）用于表征碳纳米管及其对肺上皮细胞的慢性作用的微流体聚二甲基硅氧烷组织生物反应器。REU参与者与教师和研究生合作开展研究，并接受现代科学设备（AFM，X射线反射率和衍射，毛细管电泳，光刻，SEM等）的培训。和/或在计算机建模软件的使用中。 该项目包括培养未来科学领导者的重要培训，例如科学道德，实验室安全，沟通，协作和技术演示技能。非技术总结：本科生参与者（每年10名）在这个本科生研究经验（REU）网站被整合到科学研究中，以培养下一代美国科学家和工程师。该项目主要支持妇女、代表性不足的少数民族、美国武装部队退伍军人和来自经济贫困地区的人（例如，阿巴拉契亚）。 参与将提高参与者报名参加研究生水平科学和工程教育项目的可能性，从而提高美国的科学劳动力水平。参与者将获得一个全面的计划，快速推动他们实现研究独立。这种准备工作包括与纳米材料相关项目的日常研究工作，以及以下方面的培训：研究过程和尖端科学仪器;实验室安全和科学道德;以及沟通和协作。研究项目旨在最终开发新的混合电子和光子器件，这将导致新一代的生物识别，环境监测，早期疾病检测和节能设备应用。