DISSERTATION RESEARCH: Bacterial-symbiont-mediated competitive interactions among entomopathogenic nematodes

论文研究：细菌共生体介导的昆虫病原线虫之间的竞争性相互作用

• 批准号: 1310985
• 负责人: Heidi Goodrich-Blair
• 金额: $ 1.4万
• 依托单位: University of Wisconsin-Madison
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2015-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1310985&HistoricalAwards=false
• 关键词: DISSERTATION; RESEARCH; Bacterial; symbiont; mediated

The negative effects of individual species of parasites on animals have been intensively studied and can be very strong. Many animals are infested by multiple species of parasites, some of which have symbiotic microorganisms, but we know relatively little about how the interactions between parasites and their symbionts within a host may reduce or exacerbate the effects of parasitism. This project will investigate the interactions between two species of nematodes that parasitize insects and a bacterial symbiont of one of these species. Researchers will infect an insect host with nematodes, bacteria, or both to test the effect of the bacteria on the ability of the nematodes to reproduce. To investigate the underlying mechanisms, chemicals produced within the host in the different treatments will be compared for ability to induce responses in the bacteria and to inhibit the growth of the parasites. The results will broaden our knowledge of the role of parasites in natural systems and how they affect the health of animals. Previous studies have shown that bacteria within a host can influence the performance of parasites and even prevent them from successfully reproducing. This project will add to this promising new avenue for preventing or controlling parasitism. Research will also develop the parasite-bacteria system as a tool for teaching K-12 students, and train a Ph.D. student.

寄生虫各种物种对动物的负面影响已经进行了深入的研究，并且可能非常强。 许多动物被多种寄生虫感染，其中一些动物具有共生微生物，但我们对寄生虫及其共生体之间在宿主中的相互作用如何减少或加剧寄生虫的影响相对较少。 该项目将研究两种寄生昆虫的线虫和其中一种物种的细菌共生体之间的相互作用。 研究人员将感染具有线虫，细菌的昆虫宿主，或两者都检验细菌对线虫繁殖能力的影响。 为了研究潜在机制，将比较宿主在不同处理中产生的化学物质，以诱导细菌中反应并抑制寄生虫的生长的能力。结果将扩大我们对寄生虫在自然系统中的作用以及它们如何影响动物健康的知识。先前的研究表明，宿主中的细菌会影响寄生虫的性能，甚至可以阻止它们成功再现。该项目将为预防或控制寄生虫的有希望的新途径增加。研究还将开发寄生虫 - 细菌系统，作为教授K-12学生的工具，并培训A博士学位。学生。