SBIR Phase I: Regenerable Antimicrobial Coatings Containing Zinc Oxide Binders for Hydrogen Peroxide Cleaning Solutions

这个小型企业创新研究(SBIR)第一阶段项目建议开发新型聚合物涂层，即使在表面干燥后也能结合过氧化氢(HP)，从而保持表面清洁，防止微生物生长和疾病传播。这使得表面在两次清洗之间保持持久的抗菌效果。预计这些涂层表面将杀死接触表面的99.999%的微生物。惠普作为一种安全、环保和经济的抗菌剂目前正受到人们的重新关注，最近推出的几种基于惠普的商业清洁产品就证明了这一点。众所周知，医疗设施是各种传染病的温床。导致这些疾病的病原体可以栖息在医院环境的许多地方吗？不仅在医疗程序中使用的设备和设备中，而且在床栏、浴室固定装置、扶手和计算机键盘等常见表面上也是如此。生活在这些被污染的表面上的微生物，被多个人接触，导致医疗保健相关感染(HAI)的传播增加。据估计，每20名医院患者中就有1人会因为在医院接受的护理而感染HAI。该项目的更广泛的影响/商业潜力超出了将开发涂料的医疗和医院应用，在其他领域的使用潜力巨大，在消费、工业和机构市场具有广泛的实用性。多人接触日常物品会传播感染和疾病。一只肮脏的手可以感染无数的表面。揉S的眼睛或吃三明治都可能成为感染的媒介。即使是经常清洗和消毒的表面，在应用的消毒剂蒸发后也会很快重新受到污染。这种涂料会对公众健康产生重大影响的场所包括公共卫生间中的卫浴设备；餐馆、学校和其他机构中的厨房设备和桌子；家用电器；以及航空公司、邮轮和其他公共交通工具的座椅、扶手、栏杆和托盘桌子。这种涂层可以很容易地应用到现有的制造工艺中，改装到现有的设备上，甚至作为涂料出售供DIY使用。这些涂料的商业潜力是巨大的，特别是考虑到对医疗保健行业的潜在节省。减少20%的HAI？S每年可以节省720万美元，这表明花在预防措施上的钱可以转化为有意义的节省。

This Small Business Innovation Research (SBIR) Phase I project proposes to develop novel polymer coatings that bind hydrogen peroxide (HP), even after the surface has dried, thus maintaining sanitized surfaces and preventing microbial growth and the spread of disease. This allows the surface to maintain long-lasting antimicrobial effects between cleanings. It is expected that these coated surfaces will kill 99.999% of microbes that contact the surface. HP is currently receiving renewed attention as a safe, environmentally-friendly, and cost-effective antimicrobial, as evidenced by the recent introduction of several commercially-available cleaning products based on HP. Healthcare facilities are known to be breeding grounds for a variety of infectious diseases. The pathogens that cause these diseases can reside in many places in the hospital environment ? not just in devices and equipment used in medical procedures, but also from common surfaces such as bed rails, bathroom fixtures, hand rails, and computer keyboards. Microbes living on these contaminated surfaces, which are touched by multiple people, lead to increased spread of healthcare associated infections (HAIs). It is estimated that 1 in 20 hospital patients will be infected with an HAI as a direct result of the care they receive in the hospital.The broader impact/commercial potential of this project go beyond the medical and hospital applications for which the coatings will be developed and the potential for use in other areas are enormous, with broad utility in the consumer, industrial, and institutional markets. Multiple people touching everyday objects spread infection and disease. One dirty hand can infect numerous surfaces. Rubbing one?s eye or eating a sandwich can become a vector for infection. Even surfaces that are cleaned and sanitized frequently can quickly become recontaminated after the applied disinfectant has evaporated. Examples of places where such coatings would have great impact on public health include bathroom fixtures in public restrooms; kitchen equipment and tables in restaurants, schools and other institutions; home appliances; and seats, armrests, railings, and tray tables for airlines, cruise ships, and other public transportation. Such coatings could be easily implemented into existing manufacturing processes, retrofitted to existing equipment, or even sold as paints for DIY use. The commercial potential for these coatings is huge, especially in consideration of the potential savings to the healthcare industry. A 20% percent reduction in HAI?s translates into an annual savings of $7.2 million, demonstrating that money spent on preventative steps translates into meaningful savings.