SBIR Phase I: Regenerable Antimicrobial Coatings Containing Zinc Oxide Binders for Hydrogen Peroxide Cleaning Solutions

这项小型企业创新研究（SBIR）第一阶段项目建议开发新型聚合物涂层，即使在表面干燥后也能结合过氧化氢（HP），从而保持清洁表面，防止微生物生长和疾病传播。这使得表面在两次清洁之间保持持久的抗菌效果。预计这些涂层表面将杀死与表面接触的99.999%的微生物。目前，惠普作为一种安全、环保、具有成本效益的抗菌剂正重新受到关注，最近推出的几种基于惠普的商用清洁产品证明了这一点。众所周知，保健设施是各种传染病的滋生地。导致这些疾病的病原体可能存在于医院环境的许多地方？不仅在医疗过程中使用的设备和设备中，而且在常见的表面，如床栏杆、浴室固定装置、扶手和电脑键盘上。生活在这些被多人接触的污染表面上的微生物会导致医疗保健相关感染（HAIs）的传播增加。据估计，每20名住院病人中就有1人会因在医院接受治疗而直接感染HAI。该项目的广泛影响/商业潜力超出了涂料将开发的医疗和医院应用，在其他领域的使用潜力是巨大的，在消费者、工业和机构市场具有广泛的效用。多人接触日常物品会传播感染和疾病。一只脏手可以感染许多表面。摩擦?眼睛或吃三明治都可能成为感染的媒介。即使是经常清洁和消毒的表面，在消毒剂蒸发后也会很快被重新污染。此类涂料对公共卫生产生重大影响的地方包括：公共卫生间的浴室装置；餐厅、学校和其他机构的厨房设备和餐桌；家用电器;航空公司、游轮和其他公共交通工具的座椅、扶手、栏杆和小桌板。这种涂料可以很容易地应用到现有的制造过程中，改造现有的设备，甚至可以作为DIY使用的涂料出售。这些涂料的商业潜力是巨大的，特别是考虑到对医疗保健行业的潜在节省。减少20%的HAI？S相当于每年节省720万美元，这表明花在预防措施上的钱转化为有意义的节省。

This Small Business Innovation Research (SBIR) Phase I project proposes to develop novel polymer coatings that bind hydrogen peroxide (HP), even after the surface has dried, thus maintaining sanitized surfaces and preventing microbial growth and the spread of disease. This allows the surface to maintain long-lasting antimicrobial effects between cleanings. It is expected that these coated surfaces will kill 99.999% of microbes that contact the surface. HP is currently receiving renewed attention as a safe, environmentally-friendly, and cost-effective antimicrobial, as evidenced by the recent introduction of several commercially-available cleaning products based on HP. Healthcare facilities are known to be breeding grounds for a variety of infectious diseases. The pathogens that cause these diseases can reside in many places in the hospital environment ? not just in devices and equipment used in medical procedures, but also from common surfaces such as bed rails, bathroom fixtures, hand rails, and computer keyboards. Microbes living on these contaminated surfaces, which are touched by multiple people, lead to increased spread of healthcare associated infections (HAIs). It is estimated that 1 in 20 hospital patients will be infected with an HAI as a direct result of the care they receive in the hospital.The broader impact/commercial potential of this project go beyond the medical and hospital applications for which the coatings will be developed and the potential for use in other areas are enormous, with broad utility in the consumer, industrial, and institutional markets. Multiple people touching everyday objects spread infection and disease. One dirty hand can infect numerous surfaces. Rubbing one?s eye or eating a sandwich can become a vector for infection. Even surfaces that are cleaned and sanitized frequently can quickly become recontaminated after the applied disinfectant has evaporated. Examples of places where such coatings would have great impact on public health include bathroom fixtures in public restrooms; kitchen equipment and tables in restaurants, schools and other institutions; home appliances; and seats, armrests, railings, and tray tables for airlines, cruise ships, and other public transportation. Such coatings could be easily implemented into existing manufacturing processes, retrofitted to existing equipment, or even sold as paints for DIY use. The commercial potential for these coatings is huge, especially in consideration of the potential savings to the healthcare industry. A 20% percent reduction in HAI?s translates into an annual savings of $7.2 million, demonstrating that money spent on preventative steps translates into meaningful savings.