Casting Inorganic Nanostructure Arrays with 3D DNA Crystal Molds

使用 3D DNA 晶体模具铸造无机纳米结构阵列

• 批准号: 1333215
• 负责人: Peng Yin
• 金额: $ 42.68万
• 依托单位: Harvard University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-11-01 至 2017-10-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1333215&HistoricalAwards=false
• 关键词: Casting; Inorganic; Nanostructure; Arrays; 3D

This grant is for research in the fabrication of arrays of inorganic nanostructures with prescribed three-dimensional shapes using DNA crystals with programmable three-dimensional cavities as "molds". The key innovation in this work is to develop a general platform to enable the use of micron-scale porous DNA crystals as templates to control both the shape and the architectural arrangements for inorganic materials. DNA crystals with prescribed three-dimensional cavities will be assembled in one-pot or one-reactor reactions. The cavities will serve as nano-molds, and the subsequent in-situ casting of metal structures within the mold cavities will produce metal particles of prescribed shapes, and importantly, these particles will be arranged with 3 nm precision over micron-scales.The results of this research will provide a mass production methodology for metal nanostructure arrays with prescribed morphologies and with sub-10 nm fabrication resolution and 3 nm positioning precision. This will provide a generalizable platform for the nanofabrication of inorganic materials, and, in turn, enable diverse transformative applications in fields ranging from bio-sensing to energy storage and photonics. For example, the metal particle arrays could serve as an enabling platform for developing highly sensitive and multiplexed (multiple signals) biosensor arrays to detect biomedically relevant targets. The precise control of electronic junction composition, orientation, and spacing of the metal structures could facilitate high photo-conversion efficiency in photovoltaics.

这项拨款是用于研究使用具有可编程三维空腔的DNA晶体作为“模具”制造具有指定三维形状的无机纳米结构阵列。这项工作的关键创新是开发一个通用平台，使使用微米级多孔DNA晶体作为模板来控制无机材料的形状和结构安排。具有指定三维空腔的DNA晶体将在一锅或一反应器反应中组装。这些空腔将用作纳米模具，随后在模具空腔内原位铸造金属结构将产生规定形状的金属颗粒，重要的是，这些颗粒将以3 nm的精度排列在微米尺度上。这项研究的结果将提供一种大规模生产具有规定形态和亚微米尺寸的金属纳米结构阵列的方法。10 nm的制造分辨率和3 nm的定位精度。这将为无机材料的纳米纤维提供一个可推广的平台，从而在从生物传感到能量存储和光子学等领域实现各种变革性应用。例如，金属颗粒阵列可以作为开发高灵敏度和多路复用（多信号）生物传感器阵列的支持平台，以检测生物医学相关的目标。 精确控制金属结构的电子结组成、取向和间距可以促进光电子学中的高光转换效率。

项目成果

DNA Nanostructures-Mediated Molecular Imprinting Lithography

• DOI: 10.1021/acsnano.6b04777
• 发表时间: 2017-01-01
• 期刊: ACS NANO
• 影响因子: 17.1
• 作者: Tian, Cheng;Kim, Hyojeong;Liu, Haitao
• 通讯作者: Liu, Haitao