CAREER: Advancement of Microalgal Biotechnology via Quantitative Sustainable Design: An Integrated Research and Education Plan

职业：通过定量可持续设计推进微藻生物技术：综合研究和教育计划

• 批准号: 1351667
• 负责人: Jeremy Guest
• 金额: $ 40万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-05-15 至 2019-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1351667&HistoricalAwards=false
• 关键词: CAREER; Advancement; Microalgal; Biotechnology; via

PI: Guest, JeremyProposal Number: 1351667Institution: University of Illinois at Urbana-ChampaignTitle: CAREER: Advancement of Microalgal Biotechnology via Quantitative Sustainable Design: An Integrated Research and Education PlanThis project will advance the frontier of microalgal biotechnology through the integration of experimentation, modeling, and quantitative sustainable design (QSD), and will leverage this framework to improve the education and retention of a diverse student body in environmental engineering. Research will pursue energy-positive nutrient recovery from wastewater with microalgae, and will focus on overcoming critical knowledge gaps that limit our ability to design mixed community microalgal bioprocesses that might bring this transformation within reach. Objectives of the research are (i) to elucidate the mechanisms governing microalgal bioprocess performance across a landscape of possible designs, and (ii) to establish a path forward for energy positive nutrient (nitrogen and phosphorus) recovery from wastewater. Experiments with mixed communities of microalgae treating wastewater will be coupled with modeling to advance understanding of how key design parameters influence process performance, microbial community structure and function. These findings will be integrated in a QSD framework (including life cycle assessment, life cycle costing, sensitivity and uncertainty analyses) to identify technology targets and chart a path forward for microalgal wastewater biotechnology development.Research efforts will be integrated with an education plan designed (i) to increase the intrinsic motivation of minority and female students in introductory- and advanced-level environmental engineering courses through an aspirational resource management framework, and (ii) to increase awareness of and ability to navigate trade-offs among environmental, economic, and performance sustainability criteria for engineered systems. These goals will be achieved by developing two online course modules that will be designed, tested, and deployed at UIUC, Bucknell University, and Parkland College. Modules will be designed through cognitive labs and will include external, independent formative and summative evaluations.Current approaches to nutrient management at wastewater treatment plants (WWTPs) use costly, energy-intensive processes that rely on bacteria and chemicals to remove nitrogen and phosphorus. This research will re-envision nutrient management at WWTPs by utilizing native microalgae for energy-positive biological nutrient recovery. In addition to increasing the embodied chemical energy of wastewater more than 2-fold, this approach may also advance the limit of technology by overcoming the critical barrier of dissolved organic nitrogen, a form of N that is often unable to be removed by existing nutrient removal processes but which can be rapidly assimilated by microalgae. The core concept of the research plan is microalgal technology development can be expedited through integration of experimentation, modeling, and QSD. This integrated process will elucidate molecular-scale barriers to systems-scale sustainability and seek to overcome them through process design. This approach will enable the setting of targets for technology performance, and identify critical areas for future research to achieve long-term adoption and sustainability. The research activities will be coupled with educational activities to increase the attraction and retention of underrepresented students by focusing on aspirational outcomes of environmental engineering and developing a new platform for education in sustainable design.

PI：宾客，杰里米·普罗帕萨尔（JeremyProposal）编号：1351667施工：伊利诺伊大学乌尔巴纳大学 - 临时招待会：职业：通过定量可持续性设计的微藻生物技术的进步：整体研究和教育计划将通过Micro Alalgal Biotection of Micro Alalgal Biotection of Micro Alalgal Biotection和Quantival offerative and native Interiative and Interiative and Intial Intial Intial Intial Interivation and Modementive and Modelsing，模型，模型，模型，模型）这个框架以改善在环境工程领域的多元化学生团体的教育和保留。研究将追求用微藻从废水中恢复能量阳性的营养，并将集中在克服关键知识差距上，以限制我们设计混合社区微藻生物过程的能力，从而使这种转变可能触及。该研究的目标是（i）阐明在可能设计的景观中管理微藻生物过程性能的机制，以及（ii）为从废水中的能源阳性营养（氮和磷）恢复的前进道路。与微藻处理废水的混合群落的实验将与建模相结合，以促进对关键设计参数如何影响过程性能，微生物群落结构和功能的理解。这些发现将集成到QSD框架（包括生命周期评估，生命周期成本，敏感性和不确定性分析）中，以确定技术目标并为微藻废水生物技术开发的前进方向发展。研究工作将与设计（i）的教育计划集成（i），以提高培训和女性在介绍性环境中的启发性和女性的培训，并将其融合在一起。框架以及（ii）提高对工程系统环境，经济和性能可持续性标准之间对折衷权衡的认识和能力。这些目标将通过开发两个将在UIUC，Bucknell University和Parkland College设计，测试和部署的在线课程模块来实现。模块将通过认知实验室设计，并将包括外部，独立的形成性和总结性评估。废水处理厂（WWTPS）的营养管理方法（WWTPS）使用依赖细菌和化学物质的昂贵的能源密集型过程来去除氮和磷。这项研究将通过利用天然微藻进行能量阳性的生物营养恢复，在WWTPS上重新开展营养管理。除了增加废水的体现化学能超过2倍外，这种方法还可以通过克服溶解的有机氮的关键障碍来提高技术的极限，而溶解的有机氮的关键障碍物通常无法通过现有的营养清除过程来清除，但可以通过Microalgae快速吸收。研究计划的核心概念是通过整合实验，建模和QSD来加快微藻技术的开发。这个综合过程将阐明系统尺度可持续性的分子规模障碍，并试图通过过程设计克服它们。这种方法将使能够设定技术绩效的目标，并确定未来研究的关键领域，以实现长期采用和可持续性。研究活动将与教育活动相结合，以通过关注环境工程的理想成果并为可持续设计的教育提供新的平台，从而增加代表性不足的学生的吸引力和保留。