Core-Facility BioSupraMol, Core-Facility and competence network

BioSupraMol 核心设施、核心设施和能力网络

• 批准号: 213868804
• 负责人: Professor Dr. Rainer Haag
• 金额: --
• 依托单位: Abteilung Organische Chemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2012
• 资助国家: 德国
• 起止时间: 2011-12-31 至 2020-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/213868804?language=en
• 关键词: Core; Facility; BioSupraMol; competence; network

The Core Facility BioSupraMol links research activities in the field of Supramolecular Chemistry and Structural Biology at the Freie Universität Berlin. The original four units have now been extended to include further analytical and preparative methods, such as advanced light microscopy techniques, X-ray crystallography and microfluidics. In the second funding phase, this expansion shall be further consolidated by a new data management platform and made internationally even more visible by continuing the Summer School program. The sustainable management and analysis of research data, whose volume is already in the terabyte range per week will significantly increase in particular with the implementation of new high resolution imaging techniques, e.g. life-cell imaging (2-Photonen). In a first project phase we will focus our efforts on data management and analysis using image data of a new cryo-TEM as pilot scheme. In the second phase, we will transfer and extend the concept towards other facilities within BioSupraMol. We expect this to be a stepwise process. Together with the facility users and operators more relevant aspects should be identified and corresponding services developed.

核心设施BioSupraMol将柏林自由大学的超分子化学和结构生物学领域的研究活动联系起来。最初的四个单元现在已经扩展到包括进一步的分析和制备方法，如先进的光学显微镜技术，X射线晶体学和微流体学。在第二个资助阶段，这一扩展将通过新的数据管理平台进一步巩固，并通过继续暑期学校计划在国际上更加引人注目。研究数据的可持续管理和分析，其数量已经在每周TB的范围内，将大大增加，特别是随着新的高分辨率成像技术的实施，如生命细胞成像（2-Photonen）。在第一个项目阶段，我们将集中精力进行数据管理和分析，使用新的低温TEM图像数据作为试点计划。在第二阶段，我们将把这一概念转移并扩展到BioSupraMol的其他设施。我们预计这将是一个逐步的过程。应与设施使用者和经营者一起确定更相关的方面，并开发相应的服务。

项目成果

Gas-phase organocatalysis with crown ethers

• DOI: 10.1039/c2sc00796g
• 发表时间: 2012-03
• 期刊: Chemical Science
• 影响因子: 8.4
• 作者: H. D. Winkler;Egor V. Dzyuba;A. Springer;Luisa Losensky;C. Schalley

Investigations of Host–Guest Interactions with Shape-Persistent Nonionic Dendritic Micelles

• DOI: 10.1021/jp401503y
• 发表时间: 2013-05
• 期刊: Journal of Physical Chemistry C
• 影响因子: 3.7
• 作者: R. Tyagi;S. Malhotra;A. Thünemann;A. Sedighi;Marcus Weber;Andreas Schäfer;R. Haag

Generation of a dynamic system of three-dimensional tetrahedral polycatenanes.

• DOI: 10.1002/anie.201209708
• 发表时间: 2013-05-27
• 期刊: Angewandte Chemie (International ed. in English)
• 作者: Black SP;Stefankiewicz AR;Smulders MM;Sattler D;Schalley CA;Nitschke JR;Sanders JK
• 通讯作者: Sanders JK