Conference: Plant Genome Stability and Change

会议：植物基因组稳定性与变化

• 批准号: 1439346
• 负责人: Anne Britt
• 金额: $ 1.02万
• 依托单位: University of California-Davis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2015-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1439346&HistoricalAwards=false
• 关键词: Conference; Plant; Genome; Stability; Change

The stability of DNA allows an organism to live and reproduce, but changes in the genome provide a means for the evolution of a species in response to a changing environment. Plant breeding has always relied on changes in DNA for generating the genetic variation needed to develop new varieties. Some of these changes in the genome occur in a controlled manner during normal seed development, but this can also occur following DNA damage after exposure to excessive light, ozone and UV. Biotechnological manipulation of the plant genome has allowed us to induce controlled genomic changes in plants, providing a huge potential for molecularly designed plant breeding. Research by the more than 80 laboratories in this field continues to rapidly expand the understanding of how plants deal with environmental and endogenous threats to their growth, development, and genomic stability, to advance the long-standing goals of gene targeting and site-directed mutagenesis of plants, and to develop technologies for the acceleration of plant breeding. Individuals with previous training and experience in repair and recombination, who have moved into plant models, have created a dynamic and productive new discipline.This proposal is to help support travel for 10 young scientists to attend a conference on Plant Genome Stability and Change is scheduled for July 17-20, 2014 at the Asilomar Conference Center, in Pacific Grove, California. The meeting plans to bring together an international group of senior and junior investigators, postdocs and graduate students working in or interested in the area of DNA repair and epigenetics and expose them to cutting-edge science via talks and posters. The meeting venue is also expected to promote lively and wide-ranging discussions that include all attendees, after talks and in more informal settings. The organizers plan to encourage, to the fullest extent possible, participation by women and underrepresented minorities.

DNA的稳定性使生物体能够生存和繁殖，但基因组的变化为物种的进化提供了一种手段，以应对不断变化的环境。植物育种一直依赖于DNA的变化来产生开发新品种所需的遗传变异。基因组中的一些变化在正常种子发育期间以受控的方式发生，但这也可能在暴露于过量光、臭氧和紫外线后DNA损伤后发生。植物基因组的生物技术操作使我们能够诱导植物中受控的基因组变化，为分子设计的植物育种提供了巨大的潜力。该领域80多个实验室的研究继续迅速扩大对植物如何应对环境和内源性威胁的理解，以促进植物的基因靶向和定点诱变的长期目标，并开发加速植物育种的技术。个人与以前的培训和经验，修复和重组，谁进入植物模型，创造了一个充满活力和富有成效的新学科。这一建议是为了帮助支持旅行的10名年轻科学家参加会议植物基因组的稳定性和变化定于2014年7月17日至20日在阿西洛马会议中心，在太平洋格罗夫，加州。该会议计划汇集一个由高级和初级研究人员，博士后和研究生组成的国际小组，他们在DNA修复和表观遗传学领域工作或感兴趣，并通过讲座和海报使他们接触尖端科学。 预计会议地点还将促进包括所有与会者在内的活跃和广泛的讨论，在会谈后和更非正式的场合。 组织者计划尽可能鼓励妇女和代表人数不足的少数群体参加。