How is the plant genome reactivated and controlled during seed germination?

种子萌发过程中植物基因组如何重新激活和控制？

• 批准号: DP220102840
• 负责人: Prof Mathew Lewsey
• 金额: $ 29.85万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-04-28 至 2025-04-27
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220102840
• 关键词: How; plant; genome; reactivated; controlled

This project aims to determine the mechanisms by which plant genomes are regulated during seed germination. The genomes of cells in mature, inactive seeds are repressed, but later must be rapidly reactivated to allow the gene expression that drives early seedling growth and development. This project will study proteins that turn genes on and off, and how these interact with the structure of DNA, in order to understand how spatial and temporal patterns of gene expression are controlled. It will advance our understanding of genome regulatory programs controlling germination and growth, and how they vary between Arabidopsis and barley. This can improve our ability to manipulate seed behaviour which would benefit growers and producers.

该项目旨在确定植物基因组在种子萌发过程中的调节机制。在成熟的、失活的种子中，细胞的基因组被抑制，但后来必须迅速重新激活，以允许驱动早期幼苗生长和发育的基因表达。该项目将研究开启和关闭基因的蛋白质，以及这些蛋白质如何与DNA结构相互作用，以了解基因表达的空间和时间模式是如何控制的。它将促进我们对控制发芽和生长的基因组调控程序的理解，以及它们在拟南芥和大麦之间的差异。这可以提高我们操纵种子行为的能力，这将有利于种植者和生产者。