Applications of the Polonovski Reaction in the Synthesis of Bioactive Opiates

该计划将有助于培养有机和药物化学领域的高素质人才。它还将讨论为大规模制备半合成药物鸦片制剂制定改进的工艺，以支持澳大利亚的一个重要出口产业。此外，更好地了解诺伐他汀的构效关系将有助于全面寻找更好的抗癌药物。

This program will contribute to the training of highly qualified personnel in the area of organic and medicinal chemistry. It will also address the development of improved processes for the large scale preparation of semi-synthetic pharmaceutical opiates in support of one of Australia's important export industries. Furthermore, a greater understanding of the structure-activity relationships of noscapine will make a contribution to the overall search for improved anti-cancer agents.