I-Corps: TEAMS-MobileVision from Advanced Vision Labs

I-Corps：来自高级视觉实验室的 TEAMS-MobileVision

• 批准号: 1505693
• 负责人: Ashok Veeraraghavan
• 金额: $ 5万
• 依托单位: William Marsh Rice University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-12-15 至 2015-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1505693&HistoricalAwards=false
• 关键词: Corps; TEAMS; MobileVision; Advanced; Vision

Age-related macular degeneration (AMD) is a disease of the eye that is the leading cause of central vision loss in people over 50 in the US. The progress of the disease can often be unpredictable and rapid. Existing technologies (bolted to tables, bulky, operated by clinician) can evaluate AMD during clinic visits, but such visits are scheduled only once every few months. Existing clinical practices fail to detect degeneration in-between clinic visits and leave clinicians and patients guessing. This I-Corps team proposes to take advantage of the ever-growing ubiquity of camera-enabled smartphones coupled with the rapid development of computational imaging to solve the between-visit AMD progression problem and usher in a new generation of portable, low-cost, computational eye-imaging devices. The development of the mobileVision AMD imager will increase understanding of how AMD progresses and how well treatments are performing by capturing retinal images at a time scale of days rather than months. These images, coupled with their review by doctors, will enable new research directions for automatic AMD diagnosis, and may lead to the development of new, more effective clinical practices.The proposed innovation is a take-home retinal imaging system. The physician shows the patient how to use the device during a scheduled visit, and then sends the patient home with the device. The patient then uses the device to take images of his or her own retina(s). The images are automatically sent to the physician, and they can be reviewed at his or her leisure. If the patient's AMD is progressing unusually, as indicated by the images, then the doctor informs the patient, and suggests an earlier follow-up visit. The fundamental research performed under previous awards demonstrates methodologies for acquiring retinal images easily, reliably, repeatably, and with high quality from a portable retinal imaging system. This directly enables the proposed implementation of a take-home retinal imaging device.

年龄相关性黄斑变性 (AMD) 是一种眼部疾病，是美国 50 岁以上人群中央视力丧失的主要原因。 疾病的进展往往是不可预测的且迅速。 现有技术（固定在桌子上，体积庞大，由临床医生操作）可以在诊所就诊期间评估 AMD，但此类就诊每隔几个月才安排一次。现有的临床实践无法检测两次就诊之间的退化情况，导致临床医生和患者只能猜测。 I-Corps 团队提议利用日益普及的带摄像头的智能手机以及计算成像的快速发展来解决访问之间的 AMD 进展问题，并引入新一代便携式、低成本计算眼部成像设备。 mobileVision AMD 成像仪的开发将通过在数天而不是数月的时间范围内捕获视网膜图像，加深对 AMD 进展情况以及治疗效果的了解。这些图像加上医生的审查，将为自动 AMD 诊断提供新的研究方向，并可能导致新的、更有效的临床实践的发展。所提出的创新是一种带回家的视网膜成像系统。医生在预约的就诊期间向患者展示如何使用该设备，然后将患者带回家。然后患者使用该设备拍摄他或她自己的视网膜图像。图像会自动发送给医生，医生可以在闲暇时进行查看。如果患者的 AMD 进展异常（如图像所示），医生会通知患者并建议尽早进行随访。先前奖项中进行的基础研究展示了从便携式视网膜成像系统轻松、可靠、可重复地获取高质量视网膜图像的方法。这直接使得所提出的带回家视网膜成像设备的实现成为可能。