Computational Biofluids in Physiology

生理学中的计算生物流体

• 批准号: 1521930
• 负责人: James Keener
• 金额: $ 2.25万
• 依托单位: University of Utah
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-05-15 至 2016-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1521930&HistoricalAwards=false
• 关键词: Computational; Biofluids; Physiology

A conference entitled, "Computational Biofluids in Physiology 2015 (CBP 2015)", will be held at the University of Utah on May 14-15, 2015. Computational biofluids is an interdisciplinary field at the intersection of mathematics, physics, computing, engineering, and biology. Although classical biofluids problems such as low Reynolds number locomotion have been studied theoretically for decades, the studies were limited to problems that were analytically tractable. These problems can now be probed with greater depth and biological relevance using computational methods. The power of personal computing combined with development of new algorithms has led to a revival of research in biofluids. Problems in physiology relating to the function of heart valves, the mechanics of blood clotting, and the mechanics of motile cells are also now being investigated using novel applied mathematical techniques and computational models. Integrative research on these biological and physiological processes has the potential to lead to medical advances such as the prevention of heart attacks, strokes, and cancer metastasis.The applied mathematics community has played a central role in the resurgence of biofluids by developing theories, algorithms, and models aimed at answering fundamental biological and physical questions. While some in this community focus primarily on computation and numerics, others stay closer to the biology or physics of the problem at hand. This meeting on "Computational Biofluids in Physiology 2015" will bring together mix of senior and junior researchers from mathematics, computational science, and the life sciences in a small, exceptionally interactive setting. Invited speakers and poster contributors will present work on computational methods for fluid/structure interaction, cellular mechanics, locomotion, and systems physiology.

2015年5月14-15日，犹他大学将举行题为“2015生理学中的计算生物流体(CBP 2015)”的会议。计算生物流体是数学、物理、计算、工程和生物学交叉的交叉学科领域。虽然低雷诺数运动等经典生物流体问题在理论上已经研究了几十年，但这些研究仅限于分析上容易处理的问题。这些问题现在可以用计算方法以更大的深度和生物学相关性来探讨。个人计算的力量与新算法的开发相结合，导致了生物体液研究的复兴。与心脏瓣膜功能、血液凝结机制和运动细胞机制有关的生理学问题现在也在使用新的应用数学技术和计算模型进行研究。对这些生物和生理过程的综合研究有可能导致医学进步，如预防心脏病发作、中风和癌症转移。应用数学社区通过开发旨在回答基本生物和物理问题的理论、算法和模型，在生物体液的复兴中发挥了核心作用。虽然这个社区中的一些人主要关注计算和数值计算，但另一些人则更接近手头问题的生物学或物理学。这次“2015生理学中的计算生物流体”会议将把来自数学、计算科学和生命科学的高级和初级研究人员聚集在一个特别互动的小环境中。特邀演讲者和海报投稿人将介绍流体/结构相互作用、细胞力学、运动和系统生理学的计算方法方面的工作。